49ers vs Commanders odds, moneyline, over/under
Opening lines:
- Spread: 49ers -5.5
- Moneyline: 49ers -250; Commanders +205
- Total: 50.5
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49ers vs Commanders expert picks
Adam Kaufman: 49ers 31, Commanders 23
Apparently, the 49ers can lose another receiver and keep finding ways to win. Deebo Samuel's hamstring injury makes the depth chart even thinner, but Brock Purdy still has Christian McCaffrey, George Kittle and Mike Evans to help solve a Commanders defense that just struggled with Jameis Winston. Jayden Daniels gives Washington a chance to make this uncomfortable. His legs can extend drives, create explosive plays and keep San Francisco from settling into a predictable defensive afternoon. That's why I'm expecting the Commanders to contribute some points. I'm also expecting Kyle Shanahan to find enough favorable matchups to stay a step ahead. Currently, even injured, the unbeaten
49ers are the class of the NFL. Time to prove it yet again.
Michael Middlehurst-Schwartz: 49ers 35, Commanders 20
After its overtime meltdown, Washington will have the spotlight even more firmly trained on it as it takes on the undefeated 49ers in primetime. While San Francisco finally looked fallible against Seattle, the Commanders are a far cry from the kind of team that can force Kyle Shanahan's crew into making mistakes. Jayden Daniels and Co. need to show some baseline composure after last week's debacle, but even that isn't likely to be enough to keep the contest competitive.
Nicholas Brinkerhoff: 49ers 37, Commanders 23
Dan Quinn's reward for some of the worst clock management you've ever seen? A matchup against the coach that helped him engineer the worst collapse in Super Bowl history. It's fitting that Quinn and Kyle Shanahan meet in the '28-3 Bowl” this week, while questions continue to be asked about Washington's inexplicable tie against the New York Giants. And while Quinn would love nothing more than to move on from that, his club finds itself in a difficult spot against the undefeated 49ers. The 'underdogs in primetime” trend can only go so far. San Francisco wins in blowout fashion.
Where to watch Commanders at 49ers
- Matchup: 49ers vs. Commanders
- Date: Oct. 19
- Time: 8:15 p.m.
- Venue: Levi's Stadium
- Location: Santa Clara, California
- TV: ESPN, ABC
NFL Week 6 picks and predictions
- Seahawks at Broncos
- Texans at Jaguars
- Panthers at Eagles
- Steelers at Buccaneers
- Bears at Falcons
- Jets at Patriots
- Saints at Giants
- Titans at Colts
- Ravens at Browns
- Bills at Raiders
- Cardinals at Rams
- Chargers at Chiefs
- Cowboys at Packers
- Commanders at 49ers
This article originally appeared on USA TODAY: Commanders at 49ers: Predictions, picks and odds for NFL Week 6 game
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