1. Jacoby Brissett is in line for his first Ravens start: With Lamar Jackson and Tyler Huntley on injured reserve, Baltimore turned to rookie Joe Fagnano in a 33-10 loss to Jacksonville. The Ravens ran for 172 yards and scored only 10 points. Brissett's job is to keep drives alive when defenses load up on Derrick Henry.
2. Justin Herbert avoided a fracture: Now, can the Chargers protect him? Imaging came back negative on the middle finger of his non-throwing hand, and Herbert said he expects to play. The bigger matchup concern is that Houston sacked him a career-high eight times. Baltimore can make this a long night if the Chargers keep putting him in third-and-long.
3. Keep an eye on Kyle Hamilton's hip: If Baltimore's safety is limited or unavailable,
that could give Herbert more room to attack the middle of the field with quick throws. That's one way for the Chargers to take pressure off their offensive line, especially if Ladd McConkey is healthy enough to handle his usual workload.
4. Something's gotta give: Right? Los Angeles is 0-8, the NFL's only remaining winless team. Baltimore has dropped four in a row to plummet to the bottom of the AFC North after a 4-1 start. Someone will win in primetime. Unless there's a tie.
5. Home is for the birds: Baltimore is 2-11 ATS at home since the start of last season, failing to cover by 9.7 points per game, according to Evan Abram's NFL betting primer. The Ravens have failed to cover the spread in eight straight home games, which is the longest home against-the-spread skid in franchise history.
6. Primetime Herbert: With Justin Herbert, the Chargers are 18-8 ATS in primetime night games, winning six in a row outright since 2024.
Ravens vs Chargers odds, moneyline, over/under
Opening lines:
- Spread: Ravens (-3.5)
- Moneyline: Ravens -180; Chargers +150
- Total: 47.5
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Ravens vs Chargers USA TODAY expert picks
Adam Kaufman: Ravens 20, Chargers 16
I've been screaming since Week 2 on every platform I can find that the Chargers would be 0-9 entering Week 11. Am I really going to change course now just because Lamar Jackson's unavailable? No chance. Jacoby Brissett will make his first Ravens start and it remains to be seen how good he'll be but he's absolutely an immediate upgrade on rookie Joe Fagnano and likely journeyman Tyler Huntley as well. Brissett's used to a heavy passing load and maybe that will bring Zay Flowers back to life. As for the Bolts, Justin Herbert plans to play after hurting a finger on his non-throwing hand. He just took eight sacks in Houston and Baltimore's defense is fully capable of frustrating him as well. Plus, Ladd McConkey still isn't right. This may not get ugly, but it won't end well for Los Angeles.
Michael Middlehurst-Schwartz: Chargers 17-16
Is it time? The Bolts finally ended their 37-possession touchdown drought last week, and maybe the long-sought first win could be in sight. That might seem like a stretch against most teams, but facing the floundering Ravens gives Los Angeles a chance for another breakthrough. Getting Jacoby Brissett in the fold might raise Baltimore's floor a bit, but this feels like another team that's fighting against its emerging reality of a lost season.
Nicholas Brinkerhoff: Chargers 20, Ravens 15
Maybe? Finally? There's a chance? Yes, the Chargers are going to finally win a football game this week. L.A. gets to take on old friend and current Ravens head coach Jesse Minter on 'Monday Night Football' in what might be one of the worst games of the season. The Ravens are down to Jacoby Brissett at quarterback, who is tasked with guiding an already uninspiring offense. The Chargers are desperate for a win and this isn't a Ravens defense to be worried about. The stars are aligning, even though we won't be seeing many on the field.
Where to watch Chargers at Ravens
- Matchup: Ravens vs. Chargers
- Date: Nov. 16
- Time: 8:15 p.m.
- Venue: M&T Bank Stadium
- Location: Baltimore, Maryland
- TV: ESPN
Chargers at Ravens updated injury report
This article originally appeared on USA TODAY: Chargers at Ravens: Predictions, picks and odds for NFL Week 10 game
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