Bills vs Patriots odds, moneyline, over/under
Opening lines:
- Spread: Bills -3
- Moneyline: Bills -162; Patriots +136
- Total: 49.5
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Bills vs Patriots expert picks
Adam Kaufman: Bills 30, Patriots 23
I won't be the least bit surprised if the Bills blow the Patriots' doors off. How could you be? Last year's MVP runner-up, Drake Maye, has already turned the ball over seven times in three games. Still, Buffalo surrendered 31 points to both Houston and Detroit before its defense rescued a five-turnover afternoon against the Chargers. Even without A.J. Brown, Maye should find opportunities to make this interesting if he protects the ball. That's an awfully big if against a Bills team that can score in a hurry. Josh Allen and Buffalo pull away late at home.
Michael Middlehurst-Schwartz: Bills 31, Patriots 16
After shaping up to be a serious liability in the first two weeks, Buffalo's defense stepped up in a major way in an uncomfortably
close win over the Chargers. The unit can make more serious progress if it can keep Drake Maye, the NFL's turnover leader, confused. Josh Allen and the Bills' offense should be due for a bounce-back effort after Week 3's five-turnover face-plant.
Nicholas Brinkerhoff: Bills 31, Patriots 16
Something is wrong with Drake 'Drake Maye' Maye, and it's more than the weird nickname that no one can explain. It's hard to believe he'll be able to get right against the Bills, who were only slowed down by the 'Nickel City' alternate jerseys against the Chargers in Week 3. Don't expect another five-turnover day from Josh Allen's offense. Without forcing a few, New England won't be able to keep up against the division rival. Buffalo rolls at home.
Where to watch Patriots at Bills
- Matchup: Bills vs. Patriots
- Date: Oct. 4
- Time: 1:00 p.m.
- Venue: Highmark Stadium
- Location: Orchard Park, New York
- TV: CBS
NFL Week 4 picks and predictions
- Steelers at Browns
- Colts at Commanders
- Patriots at Bills
- Jaguars at Bengals
- Packers at Buccaneers
- Titans at Ravens
- Rams at Eagles
- Cardinals at Giants
- Jets at Bears
- Cowboys at Texans
- Dolphins at Vikings
- Broncos at 49ers
- Chiefs at Raiders
- Chargers at Seahawks
- Lions at Panthers
- Falcons at Saints
This article originally appeared on USA TODAY: Patriots at Bills: Predictions, picks and odds for NFL Week 4 game
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