Eagles vs Rams odds, moneyline, over/under
Opening lines:
- Spread: Rams -1.5
- Moneyline: Rams -122; Eagles +102
- Total: 47.5
Get the edge with our exclusive NFL betting picks
Eagles vs Rams expert picks
Adam Kaufman: Rams 24, Eagles 21
The Rams lost a thriller in Denver after a controversial pass-interference call erased an interception that could have sealed the win. The Eagles just got gouged by a Bears offense led by third-string quarterback Case Keenum. Both teams have reason to be irritated. I give Los Angeles the edge, helped by an extra day of rest and Matthew Stafford's ability to attack a Philadelphia defense that gave Keenum room to operate. Puka Nacua could return after missing two games, though his status remains uncertain. Even if Stafford has to lean on Davante Adams again, I trust the Rams to make more plays. Aaron Donald makes life difficult for Jalen Hurts.
Michael Middlehurst-Schwartz: Rams 24, Eagles 16
Puka Nacua's potential return can't come
soon enough for the Rams, who lack the depth at receiver and the finishing touch in the red zone to overcome the All-Pro's absence. But after some highly questionable late officiating marred what could have been a triumphant re-emergence from the preseason Super Bowl favorites, Los Angeles has a chance to prove itself against another established contender in Philadelphia. The Rams should be able to flounder an Eagles offense that has developed a bad habit of digging itself in a substantial hole on early downs and then staying put there.
Nicholas Brinkerhoff: Rams 24, Eagles 20
The Eagles have no juice in 2026. The offense isn't explosive. The defense can't get after the quarterback. And now they return home where the boo birds will be out in full force. That should only make life more difficult against Sean McVay's Rams, who feel like they had one stolen from them last week in Denver. Both teams need a win and the Rams have an extra gear they can use to get it.
Where to watch Rams at Eagles
- Matchup: Eagles vs. Rams
- Date: Oct. 4
- Time: 1:00 p.m.
- Venue: Lincoln Financial Field
- Location: Philadelphia, Pennsylvania
- TV: Fox
NFL Week 4 picks and predictions
- Steelers at Browns
- Colts at Commanders
- Patriots at Bills
- Jaguars at Bengals
- Packers at Buccaneers
- Titans at Ravens
- Rams at Eagles
- Cardinals at Giants
- Jets at Bears
- Cowboys at Texans
- Dolphins at Vikings
- Broncos at 49ers
- Chiefs at Raiders
- Chargers at Seahawks
- Lions at Panthers
- Falcons at Saints
This article originally appeared on USA TODAY: Rams at Eagles: Predictions, picks and odds for NFL Week 4 game
Information in this article was imported automatically into a template written and reviewed by a USA TODAY Sports editor. You can send feedback using this form.
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.
