Panthers vs Lions odds, moneyline, over/under
Opening lines:
- Spread: Lions -3.5
- Moneyline: Lions -200; Panthers +165
- Total: 50.5
Get the edge with our exclusive NFL betting picks
Panthers vs Lions expert picks
Adam Kaufman: Lions 30, Panthers 27
Detroit has scored exactly 31 points in each of its first three games. Unfortunately for the Lions, their defense has also made just about every opponent look capable of keeping up. That sounds like an invitation for Bryce Young and Carolina, even after the Panthers' disappointing loss in Cleveland. Young's sore ankle bears watching, though. On the other side, Carolina could be without both starting cornerbacks against Jared Goff, who has eight touchdowns and no interceptions. I expect points, and I won't dismiss a Panthers upset at home. I just trust Goff and the Lions' playmakers a little more in a shootout.
Michael Middlehurst-Schwartz: Lions 34, Panthers 20
Injuries are really piling up for Carolina, which most recently lost Pro
Bowl cornerback Jaycee Horn and offensive guard Damien Lewis for at least the near term. Maybe some relief will materialize after the Week 5 bye, but this could be another ugly matchup for the Panthers. Though the Lions are shorthanded in their own right, they have more than enough firepower to run away with this one.
Nicholas Brinkerhoff: Panthers 33, Lions 30
Carolina is playing its first home game on 'Sunday Night Football” since 2015. And while that doesn't mean anything in the grand scheme of things, it's something that shouldn't be overlooked. The Panthers fans finally have some hope after seeing Bryce Young emerge early in the season. Injuries are a storyline for both sides, but these teams are no strangers to some tight games. In the end, lean into the narrative as Carolina's crowd pushes the Panthers across the finish line.
Where to watch Lions at Panthers
- Matchup: Panthers vs. Lions
- Date: Oct. 4
- Time: 8:20 p.m.
- Venue: Bank of America Stadium
- Location: Charlotte, North Carolina
- TV: NBC
NFL Week 4 picks and predictions
- Steelers at Browns
- Colts at Commanders
- Patriots at Bills
- Jaguars at Bengals
- Packers at Buccaneers
- Titans at Ravens
- Rams at Eagles
- Cardinals at Giants
- Jets at Bears
- Cowboys at Texans
- Dolphins at Vikings
- Broncos at 49ers
- Chiefs at Raiders
- Chargers at Seahawks
- Lions at Panthers
- Falcons at Saints
This article originally appeared on USA TODAY: Lions at Panthers: Predictions, picks and odds for NFL Week 4 game
Information in this article was imported automatically into a template written and reviewed by a USA TODAY Sports editor. You can send feedback using this form.
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.
