Buccaneers vs Browns predictions, picks, odds for NFL Week 2 Sunday

Who will win the Tampa Bay Buccaneers vs Cleveland Browns NFL Week 2 game? The Cleveland Browns and Tampa Bay Buccaneers play on Sept. 20, at the Buccaneers' Raymond James Stadium in a game on the NFL Week 2 schedule. What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions

Football Zone

SEE ALL

Bengals Wire

Bengals coaches critical of Ja'Marr Chase usage vs. Bucs

SB Nation

Arizona Cardinals starting guards both on injury report ahead of Seahawks game

Ravens Wire

Early look at the Saints’ defensive depth chart against Ravens

What is the story about?

Who will win the Tampa Bay Buccaneers vs Cleveland Browns NFL Week 2 game?

The Cleveland Browns and Tampa Bay Buccaneers play on Sept. 20, at the Buccaneers' Raymond James Stadium in a game on the NFL Week 2 schedule.

What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions and NFL Week 2 picks taking in the game?

Which team has the best chance to win the game according to NFL Week 2 win probabilities?

Check out The Arizona Republic's score prediction for the Sunday football game, as well as Browns vs Buccaneers picks, odds and win chances for the NFL Week 2 game, which can be seen at 10 a.m. MST on CBS (stream with FUBO).

Watch Browns at Buccaneers on FUBO (free trial)

Tampa Bay Buccaneers vs Cleveland Browns prediction

The Arizona Republic is predicting a 31-17 win for the

Buccaneers over the Browns in the NFL Week 2 Sunday football game.

Jeremy Cluff writes: "Baker Mayfield and the Buccaneers will bounce back in a big way against the overmatched Browns."

Cleveland Browns vs Tampa Bay Buccaneers picks

Will the Buccaneers or Browns win the game in NFL Week 2?

Bookies.com says to bet the Buccaneers to cover against the Browns.

Sports Betting Dime's formula predicts a 17.1-14 win for the Buccaneers over the Browns.

Dimers.com's final score prediction? Buccaneers 24, Browns 16

Sportnaut is predicting a 31-17 win for the Buccaneers over the Browns.

Tampa Bay Buccaneers vs Cleveland Browns win probabilities

The Buccaneers have a 77.6% chance to beat the Browns, according to ESPN.

The site gives the Browns a 22.2% shot at winning the NFL Week 2 game, with the remaining percentage accounting for a tie.

Cleveland Browns vs Tampa Bay Buccaneers odds

The Buccaneers are an 8.5-point favorite over the Browns in NFL Week 2 odds for the game, courtesy of BetMGM Sportsbook.

Tampa Bay is -400 on the moneyline, while Cleveland is +320.

The over/under (point total) is set at 41 points.

Cleveland Browns linebacker Easton Mascarenas-Arnold (42) smiles while warming up before an NFL football matchup at EverBank Stadium on Sunday, Sept. 13, 2026, in Jacksonville, Fla. The Jaguars defeated the Browns 34-10. [Corey Perrine/Florida Times-Union]

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don't miss a thing.

This article originally appeared on Arizona Republic: Buccaneers vs Browns predictions, picks, odds for NFL Week 2 Sunday

Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.

Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.

Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.