The Oregon State Beavers and Houston Cougars play on Saturday, Sept. 5, 2026, at TDECU Stadium in Houston, Texas, in a game on the college football Week 1 schedule.
Which team will win the college football Week 1 game?
Check out these college football Week 1 picks and college football Week 1 predictions for the game, which can be seen at 9 a.m. MST on ESPN (stream with FUBO).
Houston is a 20.5-point favorite over Oregon State in college football Week 1 odds for the game, according to BetMGM Sportsbook.
The Cougars are -1400 on the moneyline, while the Beavers are +900. The over/under (point total) for the game is set at 51.5 points.
Watch Oregon State vs Houston on FUBO (free trial)
The Arizona Republic: Houston 38, Oregon State 17
Jeremy Cluff writes: "Houston is fourth in odds to win the Big 12.
Conner Weigman and the Cougars will show why with a big win over Oregon State at home."
Bookies.com: Bet Houston to cover vs Oregon State
Bill Speros writes: "The second spot in the Big 12 title game could belong to a half-dozen teams, including Houston. The conference can expect no more than one CFB Playoff Spot. So, big wins in non-conference games just mean more in the Big 12, too. Willie Fritz’s Cougars took a nice leap last season from 4-8 to 10-3. RB Makhi Hughes carries the load in this ball-control offense, along with QB Conner Weigman. But Houston’s defense will determine the difference between the Texas Bowl and a potential playoff berth. The Beavers begin another rebuild under new coach JaMarcus Shepherd."
Dimers.com: Houston 35, Oregon State 15
It writes: "After extensive simulations, our model gives Oregon State a win probability of 9%, while Houston has a win probability of 91%."
ESPN: Houston has a 91.3% chance to defeat Oregon State on Saturday
The site gives the Beavers an 8.7% shot at winning the college football Week 1 game.
Sports Betting Dime: Houston 28.1, Oregon State 18.7
The site's formula predicts that the Cougars will beat the Beavers in the Week 1 college football game.

College Football News: Houston 38, Oregon State 13
Pete Fiutak writes: "Oregon State will be competitive, and it’s not going to be as bad as the 2-10 version of last season, but Houston will be too sharp and explosive. It’ll be a 60-minute game, but the Cougars won’t have to deal with a ton of drama."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Oregon State vs Houston picks, predictions, odds for Week 1 game
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