The Texas Tech Red Raiders and Colorado Buffaloes play on Saturday, Oct. 3, 2026, at Folsom Field in Boulder, Colorado, in a game on the college football Week 5 schedule.
Which team will win the college football Week 5 game?
Check out these college football Week 5 picks and college football Week 5 predictions for the game, which can be seen at 4:30 p.m. MST on FOX (stream with FUBO).
Texas Tech is a 13-point favorite over Colorado in college football Week 5 odds for the game, according to BetMGM Sportsbook.
The Red Raiders are -525 on the moneyline, while the Buffaloes are +400. The over/under (point total) for the game is set at 50.5 points.
Watch Texas Tech vs Colorado on FUBO (free trial)
The Arizona Republic: Texas Tech 35, Colorado 21
Jeremy Cluff writes: "Texas Tech is still one of the teams
to beat in the Big 12 this season. Deion Sanders and Colorado have two straight losses since a 2-0 start. They will lose a third straight Saturday."
Bookies.com: Bet Texas Tech to cover vs Colorado
Bill Speros writes: "The Red Raiders hit Boulder ranked in the top 15 but with just one conference game on the scoreboard. Colorado continued its three-season-long decline with a 23-13 loss to a banged-up Baylor squad. Texas Tech's offense must improve as it begins a run of eight straight conference games that — hopefully for Joey McGuire — ends up in the Big 12 title game. Given the clutter likely atop the conference, point differential in games such as this may matter come tiebreaker time. Our model has Tech winning by 21.1 points and covering for the first time this season."
Dimers.com: Texas Tech 32, Colorado 19
It writes: "After extensive simulations, our model gives Texas Tech a win probability of 82%, while Colorado has a win probability of 18%."
ESPN: Texas Tech has an 86.9% chance to defeat Colorado
The site gives the Buffaloes a 13.1% shot at winning the college football Week 5 game.
Sports Betting Dime: Texas Tech 29.1, Colorado 17.5
The site's formula predicts that the Red Raiders will beat the Buffaloes in the Week 5 college football game.
Sporting News: Texas Tech 34, Colorado 17
Bill Bender writes: "The line dropped a point. The Buffaloes averaged 10 points through their last two losses under coach Deion Sanders. The Red Raiders have been stop-and-start on offense, and Colorado allows just 3.2 yards per carry. Will Hammond – who threw three interceptions against Sam Houston in Week 4 – will need to avoid the turnovers. Texas Tech is 4-2 ATS as a road favorite since last season."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Texas Tech vs Colorado picks, predictions for college football Week 5
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