Monday Night Football predictions, picks, odds for Chiefs vs Broncos

Who will win on Monday Night Football in NFL Week 1? The Denver Broncos and Kansas City Chiefs play on Monday, Sept. 14, at the Chiefs' Arrowhead Stadium in the final game on the NFL Week 1 schedule. What do NFL Week 1 odds say about the Monday Night Football game? Who are NFL Week 1 predictions and

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Who will win on Monday Night Football in NFL Week 1?

The Denver Broncos and Kansas City Chiefs play on Monday, Sept. 14, at the Chiefs' Arrowhead Stadium in the final game on the NFL Week 1 schedule.

What do NFL Week 1 odds say about the Monday Night Football game? Who are NFL Week 1 predictions and NFL Week 1 picks taking in the game?

Which team has the best chance to win the game according to NFL Week 1 win probabilities

?

Check out The Arizona Republic's score prediction for the Monday Night Football game, as well as Broncos vs Chiefs picks, odds and win chances for the NFL Week 1 game, which can be seen at 5:15 p.m. MST on ESPN and ABC (stream with FUBO).

NFL Week 1 picks: Patriots vs Seahawks | 49ers vs Rams | Bears vs Panthers | Buccaneers

Watch Monday Night football games on FUBO (free trial)

Monday Night Football prediction for Chiefs vs Broncos game

The Arizona Republic is predicting a 27-24 win for the Chiefs over the Broncos in the NFL Week 1 Monday Night Football game.

Jeremy Cluff writes: "Sean Payton holds a 7-4 coaching record against Andy Reid, but Reid has had an entire offseason to get ready for this game. This one could be very interesting."

Monday Night Football picks for Broncos vs Chiefs game

Will the Chiefs or Broncos win the Monday Night Football game in NFL Week 1?

Bookies.com says to bet the Broncos with the points vs Chiefs.

Sports Betting Dime's formula predicts an 18.1-11.4 win for the Broncos over the Chiefs.

Dimers.com's final score prediction? Chiefs 22, Broncos 20

BetMGM is predicting that the Chiefs will cover against the Broncos.

Monday Night Football win probabilities for Chiefs vs Broncos game

The Chiefs have a 58.5% chance to beat the Broncos on Monday Night Football, according to ESPN.

The site gives the Broncos a 41.2% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.

Monday Night Football odds for Broncos vs Chiefs game

The Chiefs are a 2.5-point favorite over the Broncos in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.

Kansas City is -145 on the moneyline, while Denver is +120.

The over/under (point total) is set at 43.5 points.

Denver Broncos quarterback Bo Nix (10) during the first quarter of a preseason game against the Green Bay Packers at Empower Field at Mile High in Denver, Colorado on Aug. 21, 2026.

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Monday Night Football predictions, picks, odds for Chiefs vs Broncos

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