The New England Patriots and Buffalo Bills play on Sunday, Oct. 4, at the Bills' Highmark Stadium in a game on the NFL Week 4 schedule.
Which team will win the NFL Week 4 game?
Check out these NFL Week 4 picks and NFL Week 4 predictions for the game, which can be seen at 10 a.m. MST on CBS (stream with FUBO).
The Bills are a 6.5-point favorite over the Patriots in NFL Week 4 odds
for the game, courtesy of BetMGM Sportsbook.Buffalo is -325 on the moneyline, while New England is +260. The over/under (point total) is set at 48.5 points.
Watch Patriots vs Bills on FUBO (free trial)
The Arizona Republic: Bills 31, Patriots 17
Jeremy Cluff writes: "This AFC East game is pivotal for the Patriots, who already find themselves chasing the undefeated Bills. New England's defense will be chasing Josh
Allen throughout this game."
Bookies.com: Bet the under in Bills vs Patriots game
Bill Speros writes: "Drake Maye's collapse continued Sunday in Jacksonville. Maye, the MVP runner-up last season, turned the ball over three times, failed to throw a TD for the second game, and posted a 48.6 QB rating. Maye may never throw the ball again. Equally inept was the Patriots' defense, which checked out during the 35-6 loss following Maye's back-breaking pick in the end zone. The Bills and Josh Allen downed the Chargers 24-16. The Bills go 3 games up on the Patriots in the AFC East with a win here. A callback: in December 2021, the Patriots visited Buffalo in a windstorm and ran the ball 47 times out of 50 snaps for a 14-10 win. Something along those lines is their only hope here. But Allen won't be held to 10 points."
Sports Betting Dime: Bills 21.8, Patriots 21.1
The site's formula predicts that the Bills will win the NFL Week 4 game against the Patriots.
ESPN: Bills have a 71% chance to beat Patriots
The site gives the Patriots a 28.8% shot at winning the NFL Week 4 game, with the remaining percentage accounting for a tie.
Dimers: Bills 27, Patriots 21
It writes: "The numbers give the Patriots a win probability of 28.7%, while the Bills have a win probability of 71.3%."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Patriots vs Bills picks, predictions, odds for NFL Week 4 game Sunday
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