Broncos vs Jaguars predictions, picks, odds for NFL Week 2 game Sunday

Who will win the Denver Broncos vs Jacksonville Jaguars NFL Week 2 game? The Jacksonville Jaguars and Denver Broncos play on Sept. 20, at the Broncos' Empower Field at Mile High in a game on the NFL Week 2 schedule. What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions an

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Who will win the Denver Broncos vs Jacksonville Jaguars NFL Week 2 game?

The Jacksonville Jaguars and Denver Broncos play on Sept. 20, at the Broncos' Empower Field at Mile High in a game on the NFL Week 2 schedule.

What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions and NFL Week 2 picks taking in the game?

Which team has the best chance to win the game according to NFL Week 2 win probabilities?

Check out The Arizona Republic's score prediction for the Sunday football game, as well as Jaguars vs Broncos picks, odds and win chances for the NFL Week 2 game, which can be seen at 10 a.m. MST on FOX (stream with FUBO).

Watch Jaguars at Broncos on FUBO (free trial)

Denver Broncos vs Jacksonville Jaguars prediction

The Arizona Republic is predicting a 27-24 win for the Broncos

over the Jaguars in the NFL Week 2 Sunday football game.

Jeremy Cluff writes: "Trevor Lawrence and the Jaguars impressed in Week 1, but its hard to win at Empower Field at Mile High."

Jacksonville Jaguars vs Denver Broncos picks

Will the Broncos or Jaguars win the game in NFL Week 2?

Bookies.com says to bet the under in the Broncos vs Jaguars game.

Sports Betting Dime's formula predicts an 18.8-18.4 win for the Jaguars over the Broncos.

Dimers.com's final score prediction? Broncos 23, Jaguars 22.

Sportnaut is predicting a 28-27 win for the Jaguars over the Broncos.

Denver Broncos vs Jacksonville Jaguars win probabilities

The Jaguars have a 53.5% chance to beat the Broncos, according to ESPN.

The site gives the Broncos a 46.2% shot at winning the NFL Week 2 game, with the remaining percentage accounting for a tie.

Jacksonville Jaguars vs Denver Broncos odds

The Broncos are a 3-point favorite over the Jaguars in NFL Week 2 odds for the game, courtesy of BetMGM Sportsbook.

Denver is -150 on the moneyline, while Jacksonville is +125.

The over/under (point total) is set at 44.5 points.

Jacksonville Jaguars running back Bhayshul Tuten (33) signals a first down during the second quarter of an NFL football matchup at EverBank Stadium on Sunday, Sept. 13, 2026, in Jacksonville, Fla. The Jaguars defeated the Browns 34-10. [Corey Perrine/Florida Times-Union]

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Broncos vs Jaguars predictions, picks, odds for NFL Week 2 game Sunday

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