The Florida State Seminoles and Alabama Crimson Tide play on Saturday, Sept. 19, 2026, at Brant-Denny Stadium in Tuscaloosa, Alabama, in a game on the college football Week 3 schedule.
Which team will win the college football Week 3 game?
Check out these college football Week 3 picks and college football Week 3 predictions for the game, which can be seen at 12:30 p.m. MST on ABC (stream with FUBO).
Alabama is a 19.5-point favorite over Florida State in college football Week 3 odds for the game, according to BetMGM Sportsbook.
The Crimson Tide are -1400 on the moneyline, while the Seminoles are +950. The over/under (point total) for the game is set at 49.5 points.
Watch Alabama vs Florida State on FUBO (free trial)
Sportsbook Review: Bet Florida State with the points vs Alabama
Mike Spector writes: "Mike Spector writes: Florida
State is coming off a mini bye week after having last played on Labor Day Monday, and that extra rest should factor in here. The Seminoles allowed SMU quarterback Kevin Jennings to throw for a career-high 430 yards, but slinging it all over the yard hasn’t been Alabama’s identity."
Bookies.com: Bet the over in Alabama vs Florida State game
Bill Speros writes: "The Tide looked scary good at Kroger Field Saturday. Renegade might want to stay in his stable for this one. Florida State comes off an early-season bye. FSU will be challenged to score here. Don't expect any let up, even in a non-conference game."
Big 12 football Week 3 picks: Houston vs Texas Tech | Tulane vs Kansas State | Bowling Green vs Iowa State | Arizona State vs Kansas | Utah State vs Utah | BYU vs Colorado State | West Virginia vs Virginia | Colorado vs Northwestern | Northern Illinois vs Arizona | The Republic's predictions
Dimers.com: Alabama 35, Florida State 15
It writes: "After extensive simulations, our model gives Florida State a win probability of 7%, while Alabama has a win probability of 93%."
ESPN: Alabama has an 88.9% chance to defeat Florida State on Saturday
The site gives the Seminoles an 11.1% shot at winning the college football Week 3 game.
Sports Betting Dime: Florida State 24.3, Alabama 23.8
The site's formula predicts that the Seminoles will beat the Crimson Tide in the Week 3 college football game.

Stat Salt: Bet Alabama to cover vs Florida State
Kim Smith writes: "Florida State has an opportunity to show genuine improvement, but this is a massive jump in difficulty and the game is being played in Tuscaloosa. Alabama just demonstrated its ability to overcome a poor first half and completely dominate after halftime, scoring 32 unanswered points at Kentucky."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Florida State vs Alabama picks, predictions, odds for Week 3 game
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