The South Carolina Gamecocks and Florida Gators play on Saturday, Oct. 10, 2026, at Ben Hill Griffin Stadium in Gainesville, Florida, in a game on the college football Week 6 schedule.
Which team will win the college football Week 6 game?
Check out these college football Week 6 picks and college football Week 6 predictions for the game, which can be seen at 9:45 a.m. MST on SEC Network (stream with FUBO
).Florida is a 13-point favorite over South Carolina in college football Week 6 odds for the game, according to BetMGM Sportsbook.
The Gators are -500 on the moneyline, while the Gamecocks are +400. The over/under (point total) for the game is set at 62.5 points.
Watch South Carolina vs Florida on FUBO (free trial)
Sporting News: Florida 35, South Carolina 24
Bill Bender writes: "It's on Florida
to bounce back after the loss against Missouri. South Carolina leads the SEC with 256 rushing yards per game — but the Gamecocks are at a breaking point at The Swamp, where South Carolina hasn't won since 2014."
Bookies.com: Bet the over in Florida vs South Carolina game
Bill Speros writes: "Our model gives South Carolina slight value here, with Florida winning by 13.7 points against a 14.5-point line. Florida ate the rat poison after its dominant win over Ole Miss. The result: a 45-17 loss at Missouri. South Carolina offers the perfect cure for any hangover. The Gamecocks blew a 17-point lead in a 35-34 loss to Kentucky, and Shane Beamer's coaching seat remains en fuego. These programs are headed in opposite directions. Expect Jon Sumrall to laser-focus on the multiple mistakes his Gators committed at Columbia. Florida uses this one as a get-fixed opportunity before back-to-back games against Georgia and Texas. Points aplenty in The Swamp this week."
Dimers.com: Florida 38, South Carolina 24
It writes: "The numbers give South Carolina a win probability of 15.1%, while Florida has a win probability of 84.9%."
ESPN: Florida has a 73% chance to defeat South Carolina
The site gives the Gamecocks a 27% shot at winning the college football Week 6 game.
Sports Betting Dime: Florida 37.9, South Carolina 28.8
The site's formula predicts that the Gators will beat the Gamecocks in the Week 6 college football game.
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: South Carolina vs Florida picks, predictions, odds for Week 6 game
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