Patriots vs Steelers predictions, picks, odds for NFL Week 2 Sunday

Who will win the New England Patriots vs Pittsburgh Steelers NFL Week 2 game? The Pittsburgh Steelers and New England Patriots play on Sept. 20, at the Patriots' Gillette Stadium in a game on the NFL Week 2 schedule. What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions a

Football Zone

SEE ALL

SB Nation

NFL Week 2 Game Picks

Jaguars Wire

Jaguars take 'rare' approach on defense in Week 1 win

Raiders Wire

Raiders vs Chargers Week 2 TV broadcast map

What is the story about?

Who will win the New England Patriots vs Pittsburgh Steelers NFL Week 2 game?

The Pittsburgh Steelers and New England Patriots play on Sept. 20, at the Patriots' Gillette Stadium in a game on the NFL Week 2 schedule.

What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions and NFL Week 2 picks taking in the game?

Which team has the best chance to win the game according to NFL Week 2 win probabilities

?

Check out The Arizona Republic's score prediction for the Sunday football game, as well as Steelers vs Patriots picks, odds and win chances for the NFL Week 2 game, which can be seen at 10 a.m. MST on CBS (stream with FUBO).

NFL Week 2 predictions: Bills vs Lions | Falcons vs Panthers | Ravens vs Saints | Bears vs Vikings | Texans

Watch Steelers at Patriots on FUBO (free trial)

New England Patriots vs Pittsburgh Steelers prediction

The Arizona Republic is predicting a 27-19 win for the Patriots over the Steelers in the NFL Week 2 Sunday football game.

Jeremy Cluff writes: "The Patriots have had a long time to prep for this game after their lackluster Week 1 showing on Sept. 9. Drake Maye will look a lot better at home."

Pittsburgh Steelers vs New England Patriots picks

Will the Patriots or Steelers win the game in NFL Week 2?

Bookies.com says to bet the Steelers with the points against the Patriots.

Sports Betting Dime's formula predicts a 29-14-8 win for the Patriots over the Steelers.

Dimers.com's final score prediction? Patriots 24, Steelers 18

Sportnaut is predicting a 20-17 win for the Patriots over the Steelers.

New England Patriots vs Pittsburgh Steelers win probabilities

The Patriots have a 65.9% chance to beat the Steelers, according to ESPN.

The site gives the Steelers a 33.9% shot at winning the NFL Week 2 game, with the remaining percentage accounting for a tie.

Pittsburgh Steelers vs New England Patriots odds

The Patriots are a 5-point favorite over the Steelers in NFL Week 2 odds for the game, courtesy of BetMGM Sportsbook.

New England is -235 on the moneyline, while Pittsburgh is +195.

The over/under (point total) is set at 42 points.

Sep 13, 2026; Pittsburgh, Pennsylvania, USA; Pittsburgh Steelers linebacker T.J. Watt (90) during the third quarter against the Atlanta Falcons at Acrisure Stadium. Mandatory Credit: Barry Reeger-Imagn Images

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don't miss a thing.

This article originally appeared on Arizona Republic: Patriots vs Steelers predictions, picks, odds for NFL Week 2 Sunday

Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.

Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.

Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.