Chargers vs Raiders predictions, picks, odds for NFL Week 2 Sunday

Who will win the Los Angeles Chargers vs Las Vegas Raiders NFL Week 2 game? The Las Vegas Raiders and Los Angeles Chargers play on Sept. 20, at the Chargers' SoFi Stadium in a game on the NFL Week 2 schedule. What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions and NFL W

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Who will win the Los Angeles Chargers vs Las Vegas Raiders NFL Week 2 game?

The Las Vegas Raiders and Los Angeles Chargers play on Sept. 20, at the Chargers' SoFi Stadium in a game on the NFL Week 2 schedule.

What do NFL Week 2 odds say about the Sunday game? Who are NFL Week 2 predictions and NFL Week 2 picks taking in the game?

Which team has the best chance to win the game according to NFL Week 2 win probabilities

?

Check out The Arizona Republic's score prediction for the Sunday football game, as well as Raiders vs Chargers picks, odds and win chances for the NFL Week 2 game, which can be seen at 10 a.m. MST on FOX (stream with FUBO).

NFL Week 2 predictions: Bills vs Lions | Falcons vs Panthers | Ravens vs Saints | Bears vs Vikings | Texans vs Bengals

Watch Raiders at Chargers on FUBO (free trial)

Los Angeles Chargers vs Las Vegas Raiders prediction

The Arizona Republic is predicting a 23-20 win for the Chargers over the Raiders in the NFL Week 2 Sunday football game.

Jeremy Cluff writes: "The Chargers won't drop a second straight game as a big favorite to open the season, right? Justin Herbert and company bound back here."

Las Vegas Raiders vs Los Angeles Chargers picks

Will the Chargers or Raiders win the game in NFL Week 2?

Bookies.com says to bet the Raiders with the points against the Chargers.

Sports Betting Dime's formula predicts a 22.3-6.2 win for the Chargers over the Raiders.

Dimers.com's final score prediction? Chargers 25, Raiders 18

Sportnaut is predicting a 28-24 win for the Chargers over the Raiders.

Los Angeles Chargers vs Las Vegas Raiders win probabilities

The Chargers have a 68.7% chance to beat the Raiders, according to ESPN.

The site gives the Raiders a 31.1% shot at winning the NFL Week 2 game, with the remaining percentage accounting for a tie.

Las Vegas Raiders vs Los Angeles Chargers odds

The Chargers are a 6.5-point favorite over the Raiders in NFL Week 2 odds for the game, courtesy of BetMGM Sportsbook.

Los Angeles is -325 on the moneyline, while Las Vegas is +260.

The over/under (point total) is set at 43.5 points.

Sep 13, 2026; Paradise, Nevada, USA; Las Vegas Raiders defensive end Kwity Paye (95) reacts in the first quarter against the Miami Dolphins at Allegiant Stadium. Mandatory Credit: Kirby Lee-Imagn Images

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Chargers vs Raiders predictions, picks, odds for NFL Week 2 Sunday

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