How many games will the Arizona Cardinals win in the 2026 NFL regular season?
ESPN Analytics has revealed its Matchup Predictor numbers for the 17 games in the upcoming season, and they offer some interesting win probabilities, potentially seeing a difficult season ahead for Arizona.
Take a look at the site's picks for the Cardinals' game each week, beginning with the season-opening NFL Week 1 game at the Los Angeles Chargers and ending with the NFL Week 18 game against the San Francisco 49ers.
How correct will the analytics end up being?
The site allows for the possibility of ties, so the numbers add up to just less than 100%. Arizona's bye week is in Week 14.
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Cardinals NFL Week 1 prediction: At Los Angeles Chargers
Cardinals have an 18.8% chance to beat the Chargers
in NFL Week 1.
The site gives the Chargers an 81.1% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-1
Cardinals NFL Week 2 prediction: Seattle Seahawks
Cardinals have a 23.2% chance to beat the Seahawks in NFL Week 2.
The site gives the Seahawks a 76.6% shot at winning the NFL Week 2 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-2
Cardinals NFL Week 3 prediction: At San Francisco 49ers
Cardinals have an 18.8% chance to beat the 49ers in NFL Week 3.
The site gives the 49ers an 81% shot at winning the NFL Week 3 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-3
Cardinals NFL Week 4 prediction: At New York Giants
Cardinals have a 30% chance to beat the Giants in NFL Week 4.
The site gives the Giants a 69.7% shot at winning the NFL Week 4 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-4
Cardinals NFL Week 5 prediction: Detroit Lions
Cardinals have a 28.6% chance to beat the Lions in NFL Week 5.
The site gives the Lions a 71.2% shot at winning the NFL Week 5 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-5
Cardinals NFL Week 6 prediction: At Los Angeles Rams
Cardinals have a 13.7% chance to beat the Rams in NFL Week 6.
The site gives the Rams an 86.1% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-6
Cardinals NFL Week 7 prediction: Denver Broncos
Cardinals have a 32.6% chance to beat the Broncos in NFL Week 7.
The site gives the Broncos a 67.1% shot at winning the NFL Week 7 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-7
Cardinals NFL Week 8 prediction: At Dallas Cowboys
Cardinals have a 23.8% chance to beat the Cowboys in NFL Week 8.
The site gives the Cowboys a 76% shot at winning the NFL Week 8 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-8
Cardinals NFL Week 9 prediction: At Seattle Seahawks
Cardinals have an 18.1% chance to beat the Seahawks in NFL Week 9.
The site gives the Seahawks an 81.7 % shot at winning the NFL Week 9 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-9
Cardinals NFL Week 10 prediction: Los Angeles Rams
Cardinals have a 20.3% chance to beat the Rams in NFL Week 11.
The site gives the Rams a 79.6% shot at winning the NFL Week 11 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-10
Cardinals NFL Week 11 prediction: At Kansas City Chiefs
Cardinals have a 21.6% chance to beat the Chiefs in NFL Week 11.
The site gives the Chiefs a 78.2% shot at winning the NFL Week 12 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-11
Cardinals NFL Week 12 prediction: Washington Commanders
Cardinals have a 39.7% chance to beat the Commanders in NFL Week 12.
The site gives the Commanders a 60% shot at winning the NFL Week 12 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-12
Cardinals NFL Week 13 prediction: Philadelphia Eagles
Cardinals have a 31.1% chance to beat the Eagles in NFL Week 13.
The site gives the Eagles a 68.6% shot at winning the NFL Week 13 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 0-13
Cardinals NFL Week 15 prediction: New York Jets
Cardinals have a 58.5% chance to beat the Jets in NFL Week 15.
The site gives the Jets a 41.1% shot at winning the NFL Week 15 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 1-13
Cardinals NFL Week 16 prediction: At New Orleans Saints
Cardinals have a 38% chance to beat the Saints in NFL Week 16.
The site gives the Saints a 61.7% shot at winning the NFL Week 16 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 1-14

Cardinals NFL Week 17 prediction: Las Vegas Raiders
Cardinals have a 51.6% chance to beat the Raiders in NFL Week 17.
The site gives the Raiders a 48% shot at winning the NFL Week 17 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 2-14
Cardinals NFL Week 18 prediction: San Francisco 49ers
Cardinals have a 27.8% chance to beat the 49ers in NFL Week 18.
The site gives the 49ers a 72% shot at winning the NFL Week 18 game, with the remaining percentage accounting for a tie.
Cardinals predicted record: 2-15
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Arizona Cardinals predictions, picks, win probabilities for 2026 games











