The Auburn Tigers and Tennessee Volunteers play on Saturday, Oct. 3, 2026, at Neyland Stadium in Knoxville, Tennessee, in a game on the college football Week 5 schedule.
Which team will win the college football Week 5 game?
Check out these college football Week 5 picks and college football Week 5 predictions for the game, which can be seen at 12:30 p.m. MST on ESPN (stream with FUBO).
Tennessee is a 7-point favorite over Auburn in college football Week 5 odds for the game, according to BetMGM Sportsbook.
The Volunteers are -285 on the moneyline, while the Tigers are +230. The over/under (point total) for the game is set at 53.5 points.
Watch Auburn vs Tennessee on FUBO (free trial)
Sporting News: Tennessee 30, Auburn 24
Bill Bender writes: "Who protects the quarterback better? Auburn quarterback Byrum
Brown has taken 14 sacks this season — including seven in a loss to Florida in Week 3. Tennessee quarterback Faizon Brandon took 10 sacks in the Week 4 loss to Texas. It's a natural get-right spot for the Vols, but the Tigers allow just 3.1 yards per carry. These classic SEC schools have not met since 2020, and Auburn has played in three one-score games under first-year coach Alex Golesh."
Bookies.com: Bet Tennessee to cover vs Auburn
Bill Speros writes: "The Vols' Alamo-like effort fell short at Checkered Neyland against Texas in a thriller on Saturday. But they grabbed the backdoor cover of 5.5 points in the 20-17 loss. There are no soft games in the SEC, but getting Auburn at home after such a physically and emotionally draining loss helps here. The Tigers avoided an early SEC washout with a claw-and-paw 21-15 home win over Vanderbilt. Our model has Tennessee winning by 11. The Vols' offense delivers at home and gives the locals a cover."
Dimers.com: Tennessee 31, Auburn 24
It writes: "After extensive simulations, our model gives Auburn a win probability of 28%, while Tennessee has a win probability of 72%."
ESPN: Tennessee has a 71% chance to defeat Auburn
The site gives the Tigers a 29% shot at winning the college football Week 5 game.
Sports Betting Dime: Tennessee 33.2, Auburn 20.9
The site's formula predicts that the Volunteers will beat the Tigers in the Week 5 college football game.

Picks and Parlays: Bet Tennessee to cover vs Auburn
Kim Smith writes: "Tennessee has the more convincing statistical profile through the early portion of the season. The Volunteers are scoring nearly 48 points per game, averaging more than 500 yards, and have been dominant on the ground while allowing only 14 points per contest. Auburn has enough offensive balance to make this competitive early, but Tennessee’s rushing advantage and home field should become increasingly important as the game progresses. I’ll lay the points with the Volunteers."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Auburn vs Tennessee picks, predictions, odds for Week 5 game Saturday
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