The Ohio State Buckeyes and Indiana Hoosiers play on Saturday, Oct. 17, 2026, at Memorial Stadium in Bloomington, Indiana, in a game on the college football Week 7 schedule.
Which team will win the college football Week 7 game?
Check out these college football Week 7 picks and college football Week 7 predictions for the game, which can be seen at 9 a.m. MST on FOX (stream with FUBO).
Ohio State is a 3.5-point favorite over Indiana in college football Week 7 odds for the game, according to BetMGM Sportsbook.
The Buckeyes are -185 on the moneyline, while the Hoosiers are +150. The over/under (point total) for the game is set at 50.5 points.
Watch Ohio State vs Indiana on FUBO (free trial)
The Sporting News: Ohio State 31, Indiana 21
Bill Bender writes: "Can Indiana beat the Buckeyes with the same
formula as last season? Ohio State has allowed 2.9 yards per carry the last two weeks — and that's going to press Josh Hoover into making some third-down plays in the passing game. Hoover delivered against Nebraska, but Ohio State can score, too. Jeremiah Smith had eight catches for 144 yards in last year's matchup."
Bookies.com: Bet Ohio State to cover vs Indiana
Bill Speros writes: "The past two national champions have one loss combined this season (OSU to Texas). But the edge here belongs to the Buckeyes when it comes to the betting line. The 6-0 Hoosiers are just 1-5 ATS this season. And despite winning 22 straight outright, IU has posted a tepid 12-10 record ATS during that span. Our model rates this as a coin toss, with Indiana winning by a whopping 0.6 points. Indiana remains a tempting value play against the number. But their ATS number flashes red. The Bucks (5-1/4-2 ATS) re-assert Big Ten primacy in a hard-fought but decisive road victory."
Dimers.com: Ohio State 27, Indiana 24
It writes: "The numbers give Ohio State a win probability of 61.9%, while Indiana has a win probability of 38.1%."
ESPN: Ohio State has a 52.2% chance to defeat Indiana
The site gives the Hoosiers a 47.8% shot at winning the college football Week 7 game.
Sports Betting Dime: Ohio State 34.8, Indiana 26.8
The site's formula predicts that the Buckeyes will beat the Hoosiers in the Week 7 college football game.
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Ohio State vs Indiana picks, predictions, odds for Week 7 game
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