The Denver Broncos and San Francisco 49ers play on Sunday, Oct. 4, at the 49ers' Levi's Stadium in a game on the NFL Week 4 schedule.
Which team will win the NFL Week 4 game?
Check out these NFL Week 4 picks and NFL Week 4 predictions for the game, which can be seen at 1:25 p.m. MST on CBS (stream with FUBO).
The 49ers are a 3-point favorite over the Broncos in NFL Week 4 odds
for the game, courtesy of BetMGM Sportsbook.San Francisco is -150 on the moneyline, while Denver is +125. The over/under (point total) is set at 46.5 points.
Watch Broncos vs 49ers on FUBO (free trial)
The Arizona Republic: 49ers 33, Broncos 27
Jeremy Cluff writes: "Bo Nix and the Broncos' offense came alive in the second half against the Rams. They will need a complete-game effort to top Brock Purdy and the 49ers in Santa
Clara, California. We have doubts."
Bookies.com: Bet Broncos with the points vs 49ers
Bill Speros writes: "The 49ers (3-0 SU/2-1 ATS) rode the momentum from their big win Down Under over the Rams to a perfect September and first place in the NFC West. Sunday, they held off the pesky Cardinals 36-30 but missed on the 7.5-point number. San Francisco is dealing with a real injury cluster on defense — led by Nick Bosa (calf). But San Francisco's offense, led by CMC, Brock Purdy and a healthy complement of skill options, ranks 2nd in points (32.7) and 6th (393.3) in yards. Thankfully for the Broncos, defense travels. Denver's rallied from a 10-point deficit in back-to-back games for the first time in franchise history. Even Sean Payton knows that can't be sustained. This one likely comes down to a last-second kick. Take the points."
Sports Betting Dime: 49ers 27.8, Broncos 3.6
The site's formula predicts the 49ers will win the NFL Week 4 game against the Broncos.
ESPN: 49ers have a 77.6% chance to beat Broncos
The site gives the Broncos a 22.2% shot at winning the NFL Week 4 game, with the remaining percentage accounting for a tie.
Dimers: 49ers 25, Broncos 21
It writes: "The numbers give the Broncos a win probability of 36.6%, while the 49ers have a win probability of 63.4%."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Broncos vs 49ers picks, predictions, odds for NFL Week 4 game Sunday
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