Who will win the Buffalo Bills vs Los Angeles Chargers NFL Week 3 game?
The Los Angeles Chargers and Buffalo Bills play on Sept. 27, at the Bills' Highmark Stadium in a game on the NFL Week 3 schedule.
What do NFL Week 3 odds say about the Sunday game? Who are NFL Week 3 predictions and NFL Week 3 picks taking in the game?
Which team has the best chance to win the game according to NFL Week 3 win probabilities
?Check out The Arizona Republic's score prediction for the Sunday football game, as well as Chargers vs Bills picks, odds and win chances for the Week 3 NFL game, which can be seen at 10 a.m. MST on FOX (stream with FUBO).
NFL Week 3 predictions: Chargers at Bills | Panthers at Browns | Jets at Lions | Texans at Colts | Patriots at Jaguars
| Chiefs at Dolphins | Titans at Giants | Bengals at Steelers | Seahawks at Commanders | Cardinals at 49ers | Vikings at Buccaneers | Raiders at Saints | Ravens vs Cowboys | Rams at Broncos | Eagles at Bears | Win probabilities
Watch Chargers at Bills on FUBO (free trial)
Buffalo Bills vs Los Angeles Chargers prediction
The Arizona Republic is predicting a 33-17 win for the Bills over the Chargers in the NFL Week 3 Sunday football game.
Jeremy Cluff writes: "Justin Herbert and the Chargers opened the season with losses to the Cardinals and Raiders at home and now face the Bills on the road. Josh Allen and Buffalo will roll to 3-0."
Los Angeles Chargers vs Buffalo Bills picks
Will the Bills or Chargers win the game in NFL Week 3?
Bookies.com says to bet the Bills to cover against the Chargers.
Sports Betting Dime's formula predicts a 35-18.7 win for the Bills over the Chargers.
Dimers.com's final score prediction? Bills 29, Chargers 21.
Sportnaut is predicting a 31-21 win for the Bills over the Chargers.
NFL Week 3 picks: Falcons at Packers | Chargers at Bills | Panthers at Browns | Jets at Lions | Texans at Colts | Patriots at Jaguars | Chiefs at Dolphins | Titans at Giants | Bengals at Steelers | Seahawks at Commanders | Cardinals at 49ers | Vikings at Buccaneers | Raiders at Saints | Ravens vs Cowboys | Rams at Broncos | Eagles at Bears | The Republic's predictions
Buffalo Bills vs Los Angeles Chargers win probabilities
The Bills have a 78.9% chance to beat the Chargers, according to ESPN.
The site gives the Chargers a 20.9% shot at winning the NFL Week 3 game, with the remaining percentage accounting for a tie.
Los Angeles Chargers vs Buffalo Bills odds
The Bills are a 7-point favorite over the Chargers in NFL Week 3 odds for the game, courtesy of BetMGM Sportsbook.
Buffalo is -325 on the moneyline, while Los Angeles is +270.
The over/under (point total) is set at 50 points.
NFL Week 3 odds: Falcons at Packers | Chargers at Bills | Panthers at Browns | Jets at Lions | Texans at Colts | Patriots at Jaguars | Chiefs at Dolphins | Titans at Giants | Bengals at Steelers | Seahawks at Commanders | Cardinals at 49ers | Vikings at Buccaneers | Raiders at Saints | Ravens vs Cowboys | Rams at Broncos | Eagles at Bears | Point spreads, moneylines, totals for betting
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don't miss a thing.
This article originally appeared on Arizona Republic: Bills vs Chargers predictions, picks, odds for NFL Week 3 game Sunday
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.













