The UCLA Bruins and Oregon Ducks play on Saturday, Oct. 10, 2026, at Autzen Stadium in Eugene, Oregon, in a game on the college football Week 6 schedule.
Which team will win the college football Week 6 game?
Check out these college football Week 6 picks and college football Week 6 predictions for the game, which can be seen at 12:30 p.m. MST on CBS (stream with FUBO).
Oregon is an 11.5-point favorite over UCLA in college football Week 6 odds for the game, according to BetMGM Sportsbook.
The Ducks are -450 on the moneyline, while the Bruins are +360. The over/under (point total) for the game is set at 59.5 points.
Watch UCLA vs Oregon on FUBO (free trial)
Sporting News: Oregon 38, UCLA 28
Bill Bender writes: "Are the Bruins ready for Big Ten contention under first-year coach Bob Chesney?
UCLA averages 7.0 yards per carry behind a high-powered rushing attack led by Wayne Knight (445 yards, 9 TDs) and Anthony Woods (269 yards, 4 TDs). Chesney was the coach for James Madison in a 51-34 loss to the Ducks in the CFP last season. Dante Moore's status remains in question – so Dylan Raiola could be in the spotlight for the Ducks again."
Bookies.com: Bet UCLA with the points vs Oregon
Bill Speros writes: "The Big Ten's lone matchup of ranked teams this week features a pair of Pac-8/10/12 rivals. Both teams come off the bye and conference victories two weeks ago. Our model has Oregon winning by 10.5 points against a growing 13.5-point spread. Something special is brewin' this season in Pasadena. UCLA sits 4-0 ATS and is undervalued again this week. Autzen is one of the toughest environments in the country, but this 12:30 p.m. local kickoff shaves a bit off that edge. Bear down with these Bruins and take the points."
Dimers.com: Oregon 36, UCLA 23
It writes: "The numbers give UCLA a win probability of 18.1%, while Oregon has a win probability of 81.9%."
ESPN: Oregon has an 84.8% chance to defeat UCLA
The site gives the Bruins a 15.2% shot at winning the college football Week 6 game.
Sports Betting Dime: UCLA 32.2, Oregon 30.9
The site's formula predicts that the Bruins will beat the Ducks in the Week 6 college football game.
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: UCLA vs Oregon picks, predictions, odds for Week 6 game Saturday
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