The New England Patriots and Seattle Seahawks play Wednesday, Sept. 9, at the Seahawks' Lumen Field in a game on the NFL Week 1 schedule.
Which team will win the NFL Week 1 game?
Check out these NFL Week 1 picks and NFL Week 1 predictions for the game, which can be seen at 5:20 p.m. MST on NBC (stream with Peacock).
The Seahawks are a 3.5-point favorite over the Patriots in NFL Week 1 odds
for the game, courtesy of BetMGM Sportsbook.Seattle is -200 on the moneyline, while New England is +160. The over/under (point total) is set at 44.5 points.
NFL Week 1 picks: Patriots vs Seahawks | 49ers vs Rams | Bears vs Panthers | Buccaneers vs Bengals | Saints vs Lions | Bills vs Texans | Ravens vs Colts | Browns vs Jaguars | Falcons vs Steelers | Jets vs Titans
| Cardinals vs Chargers | Dolphins vs Raiders | Packers vs Vikings | Commanders vs Eagles | Cowboys vs Giants | Broncos vs Chiefs | The Republic's predictions
Watch Patriots vs Seahawks on Peacock
The Arizona Republic: Seahawks 24, Patriots 21
Jeremy Cluff writes: "The Patriots would love to get a little revenge for their Super Bowl loss to the Seahawks. Problem is, Seattle is playing at home, where they have the 12th Man. Sam Darnold will do enough to lead the champions to a season-opening win."
Bookies.com: Bet the Patriots on the moneyline vs Seahawks
Bill Speros writes: "After the Seahawks and 'The 12th Man' celebrate their Super Bowl 60 romp over the Patriots, reality awaits in the Pacific Northwest. Sam Darnold won't be catching anyone off guard this season. And he's without Kenneth Walker, who ran off to Kansas City. The Patriots, meanwhile, bulked up their offense (adding A.J. Brown) and solidified their defensive front. CB Christian Gonzalez may well be playing under duress, but that means he's auditioning for his next deal. Drake Maye under Year 2 of Josh McDaniels could be scary good. This number opened as high as Seattle -6 at some books. But sharp bettors pushed it down all the way to 3, before it settled back to 3.5. This one sets up as one of those unexpected Week 1 upsets."
Sports Betting Dime: Seahawks 21.5, Patriots 20.6
The site's formula predicts the Seahawks will win the NFL Week 1 game against the Patriots.
ESPN: Seahawks have a 61.1% chance to beat Patriots
The site gives the Patriots a 38.6% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.
Dimers: Seahawks 24, Patriots 21
It writes: "After extensive simulations, our model gives the Patriots a win probability of 39%, while the Seahawks have a win probability of 61%."
BetMGM: Bet the under in Seahawks vs Patriots game
Nick Hennion writes: "Based on the Patriots’ offensive struggles in the Super Bowl and success limiting Jaxon Smith-Njigba, my Seahawks vs Patriots prediction is the Total Under 44.5 Points (-110). A logical place to start here is asking what’s changed since the Super Bowl. In February, Seattle closed as a five-point favorite with the total set at 45.5 points. Dropping Seattle from -5 on a neutral to -3.5 at home feels slightly overactive to the offseason. Offensive questions are fair after losing Kenneth Walker, but I remain confident in the defense."
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Patriots vs Seahawks picks, predictions, odds for NFL Week 1 game
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