The Central Florida Knights and Pittsburgh Panthers play on Saturday, Sept. 12, 2026, at Acrisure Stadium in Pittsburgh, Pennsylvania, in a game on the college football Week 2 schedule.
Which team will win the college football Week 2 game?
Check out these college football Week 2 picks and college football Week 2 predictions for the game, which can be seen at 12:30 p.m. MST on ESPN (stream with FUBO).
Pittsburgh is a 7.5-point favorite over UCF in college football Week 2 odds for the game, according to BetMGM Sportsbook.
The Panthers are -285 on the moneyline, while the Knights are +230. The over/under (point total) for the game is set at 57.5 points.
Watch UCF vs Pittsburgh on FUBO (free trial)
The Arizona Republic: UCF 24, Pittsburgh 23
Jeremy Cluff writes: "The Knights took care of business
in a 73-6 win over Bethune-Cookman. Can they upset Pitt in Week 2 on the road? They can with a big game from Alonza Barnett III."
Bookies.com: Bet UCF with the points vs Pittsburgh
Bill Speros writes: "The Big 12-ACC showdown we didn’t know we needed. Scott Frost’s Knights posted a 73-6 win over FCS in-state foe Bethune-Cookman Saturday. The offensive design and tempo, however, are legit, and Pitt's defense isn't the unit that shuts that down. The Panthers win it, but they have to claw and scratch their way to do it."
Dimers.com: Pittsburgh 31, UCF 25
It writes: "After extensive simulations, our model gives UCF a win probability of 36%, while Pittsburgh has a win probability of 64%."
ESPN: Pittsburgh has a 75.4% chance to defeat UCF on Saturday
The site gives the Knights a 24.6% shot at winning the college football Week 2 game.
Sports Betting Dime: UCF 42.3, Pittsburgh 31
The site's formula predicts that the Knights will beat the Panthers in the Week 2 college football game.
Daytona Beach News-Journal: Pittsburgh will defeat UCF
The site predicts that the Panthers will beat the Knights in the college football Week 2 game on Saturday, Sept. 12, 2026.
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: UCF vs Pittsburgh picks, predictions, odds for Week 2 game Saturday
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