The NFL Week 2 schedule begins with the Detroit Lions at Buffalo Bills on Thursday Night Football at the Bills' Highmark Stadium on Sept. 17.
Here's what you need to know about how to watch the NFL Week 2 Thursday Night Football matchup tonight, including time, TV channel, streaming information and NFL Week 2 announcers for the game today.
The Lions are coming off a 31-30 overtime win against the New Orleans Saints in their NFL Week 1 game.
The Bills beat the Houston Texans, 36-31.
Detroit enters the game with 1-0 record. Buffalo is also 1-0 on the season.
NFL Week 2 predictions: Bills vs Lions | Falcons vs Panthers | Ravens vs Saints | Bears vs Vikings | Texans vs Bengals | Patriots vs Steelers | Jets vs Packers | Buccaneers vs Browns | Titans vs Eagles
| Broncos vs Jaguars | Chargers vs Raiders | Cardinals vs Seahawks | Cowboys vs Commanders | 49ers vs Dolphins | Chiefs vs Colts | Rams vs Giants | Win probabilities
Watch Rams at Seahawks on Amazon Prime Video
What time is Thursday Night Football?
The Lions vs Bills NFL Week 2 Thursday Night Football game is scheduled to begin at 5:15 p.m. MST, 8:15 p.m. ET.
NFL Week 2 picks: Lions vs Bills | Panthers vs Falcons | Saints vs Ravens | Vikings vs Bears | Bengals vs Texans | Steelers vs Patriots | Packers vs Jets | Browns vs Buccaneers | Eagles vs Titans | Jaguars vs Broncos | Raiders vs Chargers | Seahawks vs Cardinals | Commanders vs Cowboys | Dolphins vs 49ers | Colts vs Chiefs | Giants vs Rams | The Republic's predictions
What channel is Thursday Night Football on?
The Thursday Night Football NFL Week 2 game between the Bills and Lions is not on TV and is only available through streaming.
How can I stream Thursday Night Football?
The NFL Week 2 Lions at Bills Thursday Night Football game will stream exclusively on Amazon Prime Video.
NFL Week 2 odds: Lions vs Bills | Panthers vs Falcons | Saints vs Ravens | Vikings vs Bears | Bengals vs Texans | Steelers vs Patriots | Packers vs Jets | Browns vs Buccaneers | Eagles vs Titans | Jaguars vs Broncos | Raiders vs Chargers | Seahawks vs Cardinals | Commanders vs Cowboys | Dolphins vs 49ers | Colts vs Chiefs | Giants vs Rams | Betting lines, spreads
Who are the announcers for Thursday Night Football?
Al Michaels will have the play-by-play call for the Bills vs Lions TNF game in NFL Week 2, with Kirk Herbstreit as the analyst.
What's the Thursday Night Football schedule?
- NFL Week 2: Detroit Lions at Buffalo Bills, Sept. 17, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 3: Atlanta Falcons at Green Bay Packers, Sept. 24, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 4: Pittsburgh Steelers at Cleveland Browns, Oct. 1, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 5: Tampa Bay Buccaneers at Dallas Cowboys, Oct. 8, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 6: Seattle Seahawks at Denver Broncos, Oct. 15, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 7: New England Patriots at Chicago Bears, Oct. 22, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 8: Carolina Panthers at Green Bay Packers, Oct. 29, 5:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 9: Jacksonville Jaguars at Baltimore Ravens, Nov. 5, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 10: Washington Commanders at New York Giants, Nov. 12, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 11: Indianapolis Colts at Houston Texans, Nov. 19, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 12: Denver Broncos at Pittsburgh Steelers, Friday, Nov. 27, 1 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 13: Kansas City Chiefs at LA Rams, Dec. 3, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 14: Minnesota Vikings at New England Patriots, Dec. 10, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 15: San Francisco 49ers at LA Chargers, Dec. 17, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 16: Houston Texans at Philadelphia Eagles, Dec. 24, 6:15 p.m., Amazon Prime (stream with Prime Video)
- NFL Week 17: Baltimore Ravens at Cincinnati Bengals, Dec. 31 6:15 p.m., Amazon Prime (stream with Prime Video)
Sign up for Amazon Prime to watch Thursday Night Football
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: What channel is Thursday Night Football on? How to watch Lions-Bills
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