The UCF Knights and Oklahoma State Cowboys play on Saturday, Oct. 10, 2026, at Boone Pickens Stadium in Stillwater, Oklahoma, in a game on the college football Week 6 schedule.
Which team will win the college football Week 6 game?
Check out these college football Week 6 picks and college football Week 6 predictions for the game, which can be seen at 9 a.m. MST on ESPN2 (stream with FUBO).
Oklahoma State is a 9-point favorite over UCF in college football Week 6 odds for the game, according to BetMGM Sportsbook.
The Cowboys are -375 on the moneyline, while the Knights are +290. The over/under (point total) for the game is set at 53.5 points.
Watch UCF vs Oklahoma State on FUBO (free trial)
The Arizona Republic: Oklahoma State 33, UCF 20
Jeremy Cluff writes: "Oklahoma State has won three straight
since its season-opening loss against Tulsa. Drew Mestemaker and the Cowboys will make it four in a row against UCF."
Bookies.com: Bet Oklahoma State to cover vs UCF
Bill Speros writes: "Our model has the Pokes winning by 4.2 points, so the number itself favors UCF — but everything else here points the other way. The Knights played solid defense for 40 minutes at Houston, led 17-0 in the third quarter before getting shut out the rest of the way in a 27-17 loss. That's a crusher. An 11 a.m. local kick, and an OSU team coming off a bye, both scream more trouble for a UCF squad that has lost 11 straight on the road. Look for a close game early before the Cowboys gallop into the afternoon sun with the win and the late cover. The loser here kisses its slim Big 12 title game hopes goodbye."
Dimers.com: Oklahoma State 32, UCF 23
It writes: "The numbers give UCF a win probability of 22.7%, while Oklahoma State has a win probability of 77.3%."
ESPN: Oklahoma State has a 62.6% chance to defeat UCF
The site gives the Knights a 37.4% shot at winning the college football Week 6 game.
Sports Betting Dime: Oklahoma State 25.7, UCF 24.6
The site's formula predicts that the Cowboys will beat the Knights in the Week 6 college football game.
Sporting News: Oklahoma State 34, UCF 24
Bill Bender writes: "The Cowboys are coming off a bye week – and UCF will have to put pressure on Drew Mestemaker — who is 12 of 17 (70.6%) for 433 yards and three TDs and no interceptions on passes of 20 yards or more. Oklahoma State averages 46.3 points per game in its last three games. Will the Knights get Alonzo Barnett III (hamstring) back for a tough road test? UCF is 3-0 S/U as an underdog."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don't miss a thing.
This article originally appeared on Arizona Republic: UCF vs Oklahoma State picks, predictions for Big 12 football Week 6
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.













