The San Francisco 49ers and Los Angeles Rams play on Thursday, Sept. 10, at the Melbourne Cricket Ground in Melbourne, Australia, in a game on the NFL Week 1 schedule.
Which team will win the NFL Week 1
game?
Check out these NFL Week 1 picks and NFL Week 1 predictions for the game, which can be seen at 5:35 p.m. MST on Netflix.
The Rams are a 3.5-point favorite over the 49ers in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.
Los Angeles is -200 on the moneyline, while San Francisco is +165. The over/under (point total) is set at 48.5 points.
The Arizona Republic: Rams 27, 49ers 23
Jeremy Cluff writes: "The Rams are the favorite to win the Super Bowl and could have a elite defense with Aaron Donald and Myles Garrett. The defense will make a big play or two to seal a big NFC West win in Week 1 against San Francisco."
Bookies.com: Bet the 49ers with the points vs Rams
Bill Speros writes: "The Rams visit Australia to begin a season they hope — and oddsmakers believe — ends with a Super Bowl champion back home at SoFi Stadium. Reigning league MVP QB Matthew Stafford leads the team's offense. And the Defensive Player of the Year Myles Garrett anchors the defense. Hard for even Sean McVay to screw that up — presuming everyone (see Puka Nacua) stays healthy. The 49ers should play all their games 7,870 miles away from that mysterious power station near Levi's Stadium. (see Superman & Kryptonite). The 49ers have been decimated by crucial injuries in recent seasons. They should be at their best in the season-opener. Take the points. Leave the dingo. But not the baby."
Sports Betting Dime: Rams 29.4, 49ers 21.8
The site's formula predicts the Rams will win the NFL Week 1 game against the 49ers.
ESPN: Rams have a 60.5% chance to beat 49ers
The site gives the 49ers a 39.2% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.
Dimers: Rams 26, 49ers 23
It writes: "After extensive simulations, our model gives the 49ers a win probability of 38%, while the Rams have a win probability of 62%."
BetMGM: Bet the 49ers to score under 21.5 points vs Rams
Nick Hennion writes: "Based on the Rams’ offseason additions on defense and how San Francisco produced offensive success against LA, my Rams vs 49ers prediction is the 49ers Under 21.5 Points. San Francisco cleared this benchmark in both games against the Rams last year. But it should not go ignored that the 49ers faced an inconsistent secondary and dominated through the air. Mac Jones started both contests for Kyle Shanahan. It did not matter one bit as the underlying metrics paint a strong picture of San Francisco’s scheme."
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: 49ers vs Rams picks, predictions, odds for NFL Week 1 Australia game
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