The Houston Cougars and Kansas State Wildcats play on Saturday, Oct. 10, 2026, at Bill Snyder Family Stadium in Manhattan, Kansas, in a game on the college football Week 6 schedule.
Which team will win the college football Week 6 game?
Check out these college football Week 6 picks and college football Week 6 predictions for the game, which can be seen at 12:30 p.m. MST on FOX (stream with FUBO).
Kansas State is a 2.5-point favorite over Houston in college football Week 6 odds for the game, according to BetMGM Sportsbook.
The Wildcats are -145 on the moneyline, while the Cougars are +120. The over/under (point total) for the game is set at 56.5 points.
Watch Houston vs Kansas State on FUBO (free trial)
The Arizona Republic: Houston 27, Kansas State 24
Jeremy Cluff writes: "The Wildcats opened as a 2.5-point
favorite over the Cougars at home, but Conner Weigman and Houston will go into Manhattan, Kansas, and beat Kansas State to move to 5-1 overall."
Bookies.com: Bet the under in Houston vs Kansas State game
Bill Speros writes: "Houston snoozed for 30 minutes before ripping off 27 unanswered at home against UCF in a 27-17 win Saturday. The Cougars draw little energy from their own crowd. Maybe the huddled masses at Bill Snyder Family Stadium gets the Cougars motivated. K-State was once one of the biggest traps in the Big 12 — but not this year. Just ask Cincinnati. K-State's run-heavy offense and Houston's front seven both suppress scoring in this nationally televised snoozefest."
Dimers.com: Kansas State 29, Houston 27
It writes: "The numbers give Houston a win probability of 44.1%, while Kansas State has a win probability of 55.9%."
ESPN: Kansas State has a 50.9% chance to defeat Houston
The site gives the Cougars a 49.1% shot at winning the college football Week 6 game.
Sports Betting Dime: Kansas State 29, Houston 26.8
The site's formula predicts that the Wildcats will beat the Cougars in the Week 6 college football game.
Sporting News: Houston 27, Kansas State 23
Bill Bender writes: "The Wildcats had a bye week to prepare for a home shot at Houston. Kansas State allowed 271 rushing yards in a Week 4 loss against Cincinnati. The Cougars have three games with at least 200 rushing yards – and Conner Weigman ranks fourth in the Big 12 with a 166.8 passer rating. Houston is 3-0 ATS as a road underdog since last season under Willie Fritz."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Houston vs Kansas State picks, predictions for Big 12 football Week 6
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