The Northern Arizona Lumberjacks and Arizona Wildcats play on Saturday, Sept. 5, 2026, at Casino Del Sol Stadium in Tucson, Arizona, in a game on the college football Week 1 schedule.
Which team will win the college football Week 1 game?
Check out these college football Week 1 picks and college football Week 1 predictions for the game, which can be seen at 6:30 p.m. MST on ESPN+ (stream with ESPN+).
Arizona is a 33.5-point favorite over Northern Arizona in college football Week 1 odds for the game, according to BetMGM Sportsbook.
The Wildcats are -10000 on the moneyline, while the Lumberjacks are +3000. The over/under (point total) for the game is set at 57.5 points.
Watch Northern Arizona vs Arizona on ESPN+
The Arizona Republic: Arizona 41, NAU 17
Jeremy Cluff writes: "Arizona went 9-4
overall in Brent Brennan's second season. Can the Wildcats challenge for the Big 12 title in 2026? The answer might depend on how much help they give QB Noah Fifita."
Bookies.com: Bet Arizona to cover vs Northern Arizona
Bill Speros writes: "The Wildcats finished 9-4 last season but slipped among the Big 12 elite. Brent Brennan must insure all is well heading into the real schedule by handling this week’s cupcake with ease. Fifth-year QB Noah Fifita and the ‘Cats purr at home against a Big Sky in-state foe. This number isn’t outrageous - and has tightened by 2 points since it opened."
Dimers.com: Arizona 43, Northern Arizona 12
It writes: "After extensive simulations, our model gives Northern Arizona a win probability of 2%, while Arizona has a win probability of 98%."
ESPN: Arizona has a 97.1% chance to defeat NAU on Saturday
The site gives the Lumberjacks a 2.9% shot at winning the college football Week 1 game.

Arizona Daily Star: Arizona 52, NAU 17
Michael Lev writes: "The upset loss to NAU in 2021 is a distant memory; no one from that UA team is still on the roster. Arizona prevailed in the two subsequent meetings, although the 2024 matchup was a bit of a clunker offensively and foretold what was to come that season. Expect fireworks this time from a UA offense that’s been fine-tuned by second-year coordinator Seth Doege — and some mistakes by a UA secondary that’s still figuring things out. Don’t be surprised if QB Noah Fifita ties his personal best of five TD passes."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Arizona vs NAU picks, predictions, odds for college football Week 1
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