The Alabama Crimson Tide and Kentucky Wildcats play on Saturday, Sept. 12, 2026, at Kroger Field in Lexington, Kentucky, in a game on the college football Week 2 schedule.
Which team will win the college football Week 2 game?
Check out these college football Week 2 picks and college football Week 2 predictions for the game, which can be seen at 12:30 p.m. MST on ABC (stream with FUBO).
Alabama is a 10-point favorite over Kentucky in college football Week 2 odds for the game, according to BetMGM Sportsbook.
The Crimson Tide are -400 on the moneyline, while the Wildcats are +320. The over/under (point total) for the game is set at 49.5 points.
Watch Alabama vs Kentucky on FUBO (free trial)
Louisville Courier Journal: Kentucky 24, Alabama 20
Ryan Black writes: "The Wildcats stun the college football world,
jumping out to an early lead, then holding on in the final quarter to give Stein a statement win in the second game of his tenure."
Bookies.com: Bet the under in Kentucky vs Alabama game
Bill Speros writes: "QB Kenny Minchey and coach Will Stein made their UK debuts Saturday with a 45-13 win over Youngstown State. Alabama QB Keelon Russell makes his first true road start. And Kroger Field can be inhospitable for ranked SEC foes. Meanwhile, Kalen DeBoer and double-digit lines don’t mix well on the road. The Tide rolls into Lexington as 10.5-point favorites. Be wary of the hook. Since this line appears to be in constant motion, lean into the under at a set 48.5."
Dimers.com: Alabama 29, Kentucky 19
It writes: "After extensive simulations, our model gives Alabama a win probability of 77%, while Kentucky has a win probability of 23%."
ESPN: Alabama has an 84.6% chance to defeat Kentucky on Saturday
The site gives the Wildcats a 15.4% shot at winning the college football Week 2 game.
Sports Betting Dime: Alabama 29.3, Kentucky 26.3
The site's formula predicts that the Crimson Tide will beat the Wildcats in the Week 2 college football game.
SB Nation: Alabama 34, Kentucky 24
Chris Beasmore writes: "The Cats keep it close, but the Tide are able to get the victory."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Alabama vs Kentucky picks, predictions, odds for Week 2 game Saturday
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