The North Carolina Tar Heels and Pittsburgh Panthers play on Saturday, Oct. 10, 2026, at Acrisure Stadium in Pittsburgh, Pennsylvania, in a game on the college football Week 6 schedule.
Which team will win the college football Week 6 game?
Check out these college football Week 6 picks and college football Week 6 predictions for the game, which can be seen at 9 a.m. MST on ESPN (stream with FUBO).
Pittsburgh is a 4.5-point favorite over North Carolina in college football Week 6 odds for the game, according to BetMGM Sportsbook.
The Panthers are -190 on the moneyline, while the Tar Heels are +155. The over/under (point total) for the game is set at 47.5 points.
Watch North Carolina vs Pittsburgh on FUBO (free trial)
Sporting News: Pittsburgh 27, North Carolina 20
Bill Bender writes: "How will the
Panthers fare with quarterback Holden Gariner, who replaced Mason Heinstchel (torn ACL)? The Tar Heels have allowed 32.5 points per game in losses to Clemson and Notre Dame. Pitt allows just 2.0 yards per carry, and that will wear on North Carolina in the second half."
The Fayetteville Observer: North Carolina 27, Pittsburgh 23
Rodd Baxley writes: "The Panthers were dealt a devastating blow with the loss of quarterback Mason Heintschel, who tore his ACL in the win at Virginia Tech. That's a good sign for UNC's struggling secondary. Defensively, Pitt is stout and capable of creating takeaways. Still, UNC showed something in its loss against No. 3 Notre Dame. That progress will come together to produce a big road win in Pittsburgh."
Dimers.com: Pittsburgh 27, North Carolina 22
It writes: "The numbers give North Carolina a win probability of 35.8%, while Pittsburgh has a win probability of 64.2%."
ESPN: Pittsburgh has a 74.5% chance to defeat North Carolina
The site gives the Tar Heels a 25.5% shot at winning the college football Week 6 game.
Sports Betting Dime: Pittsburgh 27.7, North Carolina 16.8
The site's formula predicts that the Tar Heels will beat the Panthers in the Week 6 college football game.
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: North Carolina vs Pittsburgh picks, predictions, odds for Week 6 game
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