The San Francisco 49ers and Seattle Seahawks play on Sunday, Oct. 11, at the Seahawks' Lumen Field in a game on the NFL Week 5 schedule.
Which team will win the NFL Week 5 game?
Check out these NFL Week 5 picks and NFL Week 5 predictions for the game, which can be seen at 1:25 p.m. MST on FOX (stream with FUBO).
The Seahawks are a 3-point favorite over the 49ers in NFL Week 5 odds
for the game, courtesy of BetMGM Sportsbook.Seattle is -155 on the moneyline, while San Francisco is +130. The over/under (point total) is set at 47 points.
Watch 49ers vs Seahawks on FUBO (free trial)
The Arizona Republic: Seahawks 23, 49ers 21
Jeremy Cluff writes: "Brock Purdy and the 49ers have really impressed during their 4-0 start, but Sam Darnold and the Seahawks are at home for this game, and the 12th Man
will make a difference."
Bookies.com: Bet the 49ers with the points vs Seahawks
Bill Speros writes: "The 49ers (4-0, 3-1 ATS) powered past Denver Sunday, scoring on 3 straight possessions in the second half in a game that was tied 3-3 at the half. Brock Purdy could well game-manage this team to the NFC Championship Game. He faces his second major test this season (the 49ers beat the Rams in Week 1 Down Under) against the Super Bowl champs and the 12th Man in the Fox National Game Of The Week. San Francisco has enough balance to contend against the Seahawks' (3-1, 1-1-2 ATS) fierce defense. Seattle QB Sam Darnold saw some ghosts again in Sunday's victory over the Bolts, throwing 2 TDs and 1 pick while being sacked 3 times. The Niners make another statement this week."
Sports Betting Dime: 49ers 23.2, Seahawks 17
The site's formula predicts that the 49ers will win the NFL Week 5 game against the Seahawks.
ESPN: 49ers have a 55.4% chance to beat Seahawks
The site gives the Seahawks a 44.2% shot at winning the NFL Week 5 game, with the remaining percentage accounting for a tie.
Dimers: Seahawks 25, 49ers 23
It writes: "The numbers give the 49ers a win probability of 41.4%, while the Seahawks have a win probability of 58.6%."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: 49ers vs Seahawks picks, predictions, odds for NFL Week 5 game Sunday
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