The Arizona Wildcats and BYU Cougars play on Saturday, Sept. 12, 2026, at LaVell Edwards Stadium in Provo, Utah, in a game on the college football Week 2 schedule.
Which team will win the college football
Week 2 game?
Check out these college football Week 2 picks and college football Week 2 predictions for the game, which can be seen at 12:30 p.m. MST on FOX (stream with FUBO).
BYU is a 7.5-point favorite over Arizona in college football Week 2 odds for the game, according to BetMGM Sportsbook.
The Cougars are -295 on the moneyline, while the Wildcats are +240. The over/under (point total) for the game is set at 50.5 points.
Watch Arizona vs BYU on FUBO (free trial)
The Arizona Republic: BYU 31, Arizona 24
Jeremy Cluff writes: "This Week 2 Big 12 conference game could be intriguing, but BYU is at home, where it hasn't lost since 2024. The Cougars' defense will make some big stops on Noah Fifita and the Wildcats."
Bookies.com: Bet Arizona with the points vs BYU
Bill Speros writes: "The Big 12 Game Of The Week has the Wildcats trying to catch their breath in the altitude of Provo. A win here opens the door for Arizona’s path to the Big 12 title game. Coach Brent Brennan and QB Noah Fifita come off a nine-win season and a 35-7 tune-up over Northern Arizona on Saturday. BYU is stacked. Bear Bachmeier leads the Cougars on offense. But BYU’s defense tells the story this week. If Arizona can move the ball and avoid turnovers, this one will be closer than advertised."
Dimers.com: BYU 27, Arizona 22
It writes: "After extensive simulations, our model gives Arizona a win probability of 36%, while Brigham Young has a win probability of 64%."
ESPN: BYU has a 76.8% chance to defeat Arizona on Saturday
The site gives the Wildcats a 23.2% shot at winning the college football Week 2 game.
Sports Betting Dime: BYU 33, Arizona 17.8
The site's formula predicts that the Cougars will beat the Wildcats in the Week 2 college football game.
Sports Illustrated: BYU 34, Arizona 21
Joe Wheat writes: "The key to this game will be to speed up Fifita. In two starts against BYU, Fifita has been pressured on nearly 40% of his drop backs, completing 34% of his pressured passes, for 3.3 yards per attempt, 0 touchdowns and 3 interceptions. Assuming Nusi Taumoepeau and Tausili Akana are healthy coming in, BYU should continue to make life difficult on the Arizona signal caller. On offense, BYU is fortunate to get the Wildcats early, as an almost entirely new secondary adjusts to a new scheme and terminology. I expect Bear Bachmeier to show much better against the Wildcats this year as BYU makes a statement at home."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Arizona vs BYU picks, predictions, odds for Week 2 game Saturday
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