The Missouri Tigers and Kansas Jayhawks play on Friday, Sept. 11, 2026, at David Booth Kansas Memorial Stadium in Lawrence, Kansas, in a game on the college football Week 2 schedule.
Which team will win the college football Week 2 game?
Check out these college football Week 2 picks and college football Week 2 predictions for the game, which can be seen at 5 p.m. MST on FOX (stream with FUBO).
Missouri is a 6-point favorite over Kansas in college football Week 2 odds for the game, according to BetMGM Sportsbook.
The Tigers are -225 on the moneyline, while the Jayhawks are +190. The over/under (point total) for the game is set at 50.5 points.
Watch Missouri vs Kansas on FUBO (free trial)
The Arizona Republic: Missouri 27, Kansas 24
Jeremy Cluff writes: "This Border War game is a great game to
kick off Week 2 in Big 12 football action. Austin Simmons won't go 17-for-19 with four touchdowns like he did in Missouri's season opener, but he will lead the Tigers past the Jayhawks on the road."
Bookies.com: Bet Missouri to cover against Kansas
Bill Speros writes: "Known as the 'Border Showdown' only to network executives, school officials and sponsors, Kansas and Missouri meet for the 122nd time since 1891 in the 'Border War.' Eli Drinkwitz has back-to-back 10-win seasons and won this game 42-31 in Columbia last year. Both teams turned over their QB (Austin Simmons in for Mizzou, Isaiah Marshall for KU), but Missouri's supporting cast and defensive front are a tier above."
Dimers.com: Missouri 27, Kansas 22
It writes: "After extensive simulations, our model gives Missouri a win probability of 66%, while Kansas has a win probability of 34%."
ESPN: Missouri has a 63.2% chance to defeat Kansas on Friday
The site gives the Jayhawks a 36.8% shot at winning the college football Week 2 game.
Sports Betting Dime: Missouri 27, Kansas 21.9
The site's formula predicts that the Tigers will beat the Jayhawks in the Week 2 college football game.
Topeka Capital-Journal: Missouri 34, Kansas 24
Jordan Guskey writes: "Kansas enters this week as the underdog, and will need its fans to do their best to make Lawrence a difficult environment for an opponent to play in on Friday. But even then, for a Jayhawks team that has the potential to make a lot of strides as the season progresses, that might not be enough."
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don't miss a thing.
This article originally appeared on Arizona Republic: Missouri vs Kansas picks, predictions, odds for Week 2 game Friday
Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside. It is your sole responsibility to act in accordance with your local laws.
Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose. While we do our utmost to offer good advice and information we cannot be held responsible for any loss that may be incurred as a result of gambling. We do our best to make sure all the information that we provide on this site is correct. However, from time to time mistakes will be made and we will not be held liable. Please check any stats or information if you are unsure how accurate they are. No guarantees are made with regards to results or financial gain. All forms of betting carry financial risk and it is up to the individual to make bets with or without the assistance of information provided on this site and we cannot be held responsible for any loss that may be incurred as a result of following the betting tips provided on this site. Past performances do not guarantee success in the future and betting odds fluctuate from one minute to the next. The material contained on this site is intended to inform, entertain and educate the reader and in no way represents an inducement to gamble legally or illegally or any sort of professional advice.
Prediction Markets: Certain prediction markets are event contracts regulated by the U.S. Commodity Futures Trading Commission (CFTC) or other applicable regulatory authorities and are legally distinct from traditional gambling and sports betting. Eligibility requirements to participate in prediction markets differ from those for sports betting and gambling — you may be required to be 18 or older (or such other age as the applicable platform requires) and to satisfy other eligibility criteria established by the relevant platform and governing law. Prediction market trading involves financial risk and may not be available in all jurisdictions. The legal and regulatory status of prediction markets varies by jurisdiction and by platform. It is your sole responsibility to confirm that participation is lawful where you reside and to comply with all applicable laws and platform terms.
Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.
