The Buffalo Bills return to Highmark Stadium Sunday looking to build on one of the NFL's hottest starts. After opening the 2026 season with two convincing victories, including a primetime win over the Detroit Lions in the debut of the new Highmark Stadium, the Bills enter Week 3 as one of the AFC's early favorites.
Sunday's matchup brings a Los Angeles Chargers team heading in the opposite direction. The Chargers have stumbled out of the gate with upset losses to the Arizona Cardinals and Las Vegas Raiders and are already searching for answers.
This is a desperate and potentially dangerous opponent for the Bills because only two teams since 2002 have made the NFL playoffs after starting 0-3, a fate that is staring right at the Chargers this week.
They will be playing to essentially save their season, and that will make them a tough test for Buffalo.
The Rochester Democrat and Chronicle is bringing you live updates, scores and highlights from the game. Follow along.
Watch Bills vs. Chargers on Fubo (free trial)
What time is the Bills vs Chargers game?
10:10 AM ET, September 27 2026, Scott NorrisDate: Sunday, Sept. 27
Start time: 1p.m. ET
Where: Highmark Stadium, Orchard Park, New York.
This article originally appeared on Rochester Democrat and Chronicle: Bills vs Chargers updates, weather, how to watch and predictions for Week 3
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