Tennessee resident Brad Smith has been at the helm of two separate Nashville healthcare companies as they earned Inc. magazine recognition as the fastest-growing private businesses in the United States in recent years. The first was in 2023 with home health company Carebridge.
On Aug. 11, the magazine released its annual Inc. 5000 list naming Smith's Main Street Health as America's fastest-growing private business in 2026, according to median revenue growth rate since 2023. Main Street Health experienced 546,533% growth in its revenue and 116% employee growth over the last three years.
It is one of 104 Tennessee companies that landed on the Inc. 5000 list this year, including businesses across the healthcare, technology, logistics and entertainment
industries. Nationwide standouts include telehealth dietician Nourish, affiliate marketing platform Shop My, low-carb baked goods company Hero Bread, and the company that makes Surfside canned vodka lemonades.
In all, the Tennessee companies that made Inc.'s cut are responsible for $12.9 billion in total revenue and 35,965 employees across the state.
50 fastest-growing Tennessee companies
Here is the list of the top 50 fastest-growing Tennessee businesses in 2026, according to Inc.:
- Main Street Health, founded in 2021, based in Nashville
- True Metal Supply, founded in 2022, based in Knoxville
- Arcadia, founded in 2022, based in Nashville
- Apartment Insiders, founded in 2021, based in Nashville
- Qckbot, founded in 2021, based in Nashville
- Conduit Security, founded in 2021, based in Nashville
- Humani HR, founded in 2022, based in Nashville
- RxLogic, founded in 2020, based in Nashville
- Firecrown Media, founded in 2021, based in Chattanooga
- Tidalwave Holdings, founded in 2021, based in Chattanooga
- SeekOne Roofing Company, founded in 2021, based in Brentwood
- Majestic Photobooth, founded in 2006, based in Nashville
- MiCare Path, founded in 2019, based in Memphis
- 360 Privacy, founded in 2018, based in Brentwood
- Groups360, founded in 2014, based in Brentwood
- Dreamliner Luxury Coaches, founded in 2020, based in Whites Creek
- Infocus Clinical Research, founded in 2015, based in Brentwood
- CareHarmony, founded in 2015, based in Brentwood
- Bitfreighter, founded in 2020, based in Nashville
- Boxwood Insurance Group, founded in 2021, based in Franklin
- Spartan Fitness Holdings, founded in 2021, based in Brentwood
- Superx, founded in 2019, based in Nashville
- Big Sky Landscapes, founded in 2019, based in Chattanooga
- Talestry, founded in 2015, based in Franklin
- Country Mile, founded in 2015, based in Franklin
- Lush Enterprises, founded in 2014, based in Franklin
- CMC, founded in 2020, based in Franklin
- Moca Logistics, founded in 2018, based in Chattanooga
- RxPreferred, founded in 2011, based in Mount Juliet
- Vital Care Infusion Services, founded in 1986, based in Brentwood
- Wyre Technology, founded in 2021, based in Chattanooga
- Bolt Farm Treehouse, founded in 2015, based in Whitwell
- Center Stage Merchandising, founded in 2021, based in Nashville
- American Logistics, founded in 2020, based in Chattanooga
- LNCsearch, founded in 2020, based in Nashville
- Zach Taylor Real Estate, founded in 2021, based in Murfreesboro
- RevHD, founded in 2014, based in La Vergne
- Vanterra Foundation Solutions, founded in 1958, based in Knoxville
- PhaseWell Research, founded in 1989, based in Nashville
- Telling Ministries, founded in 2011, based in Crossville
- Kythera Labs, founded in 2019, based in Franklin
- AngelEye Health, founded in 2013, based in Nashville
- IntellaTriage, founded in 2008, based in Brentwood
- Cloud Range, founded in 2018, based in Nashville
- Crate Pros, founded in 2018, based in Lebanon
- Fortified Risk Group, founded in 2020, based in Franklin
- D1 Training, founded in 2002, based in Franklin
- TwelveStone Health Partners, founded in 2016, based in Murfreesboro
- Integrated Production Solutions, founded in 2016, based in Franklin
- RocketCert, founded in 2020, based in Knoxville
Hadley Hitson covers business news for The Tennessean. She can be reached at hhitson@tennessean.com. To support their work,subscribe to The Tennessean.
This article originally appeared on Nashville Tennessean: See Tennessee's top 50 fastest-growing businesses
