The Jacksonville Jaguars got shut down by a stout defense last week in Denver. They have to deal with another one today when the New England Patriots rumble into town.
Trevor Lawrence was held under 200 passing yards for the first time in 10 games (including last year's playoff loss), and the offense overall was stuck in the mud with just 268 yards in a 20-13 loss to the Broncos. Bhayshul Tuten continued his maturation into a lead back, though, running for a game-high 65 yards with a touchdown.
Now they get the team that beat those Broncos in last season's AFC championship game. Both come in 1-1 and sporting top-10 defenses. New England's No. 1 unit has carried the load as quarterback Drake Maye, the MVP runner-up in 2025, has struggled mightily
in the first two games this year. He's got one touchdown, four interceptions and six sacks so far.
Watch Jaguars vs. Patriots live on Fubo (free trial)
But Foye Oluokun, Josh Hines-Allen and company will have to contend with a run game that's shown it can keep games ugly and close. TreVeyon Henderson burst out for a 39-yard TD scamper in last week's 20-3 win over the Steelers, and Rhamondre Stevenson garnered 95 total yards in the season opener.
Jaguars vs Patriots odds, money line, over/under
Odds courtesy of BetMGM as of Saturday, Sept. 26.
- Moneyline: Patriots (+130) | Jaguars (-150)
- Spread: Jaguars by 3
- Over/under: 46
Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered.
Jaguars vs Patriots predictions, picks for NFL Week 3
Demetrius Harvey, Florida Times-Union
Jaguars 24, Patriots 20: "It's hard to imagine Jacksonville's offense struggling as much as it did in the second half against Denver."
Michael Middlehurst-Schwartz, USA TODAY
Jaguars 27, Patriots 20: "The Jaguars' pass rush is due to be revived after going dormant against Bo Nix, but Trevor Lawrence could be in line for a bounce-back performance to pace the passing attack."
Bill Bender, Sporting News
Patriots 20, Jaguars 19: "Drake Maye has four interceptions through two games, but the Patriots are content to run the ball with TreVeyon Henderson and Rhamondre Stevenson and lean on a defense that should give Trevor Lawrence some issues."
Jared Dubin, CBS Sports
Jaguars 23, Patriots 17: "The Jaguars' offensive has at least shown that it has an ability to be efficient and explosive at times. I think they rediscover some of that here and take care of the Patriots at home."
Jaguars vs Patriots time, TV channel today
- Kickoff time: 1 p.m. ET
- TV channel: CBS
- Livestream: Fubo (free trial) | Paramount+
This article originally appeared on Florida Times-Union: Jaguars vs Patriots predictions, picks, odds: Who wins Week 3 NFL game?
Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.













