New medications are discovered and developed through two main dimensions: effectiveness and safety, to understand their adverse effects. These validate their lasting efficacy. Every Patanjali medication gets
launched after this demanding process and thus called evidence-based.
Research for Liver Health
A study was conducted on liver cells. Allopathic and synthetic medicines can cause drug-induced liver injury (DILI), which harms the body and specially the liver. The research aimed to see if these adverse effects on the liver can be efficiently treated with Ayurvedic medicines.
When a study was done on around 1,321 patients in various US hospitals, the data showed cases of acute liver failure at a higher rate after long-term use of paracetamol and in high doses. A high rate of liver failure was seen where medicines were given during pregnancy and to treat cardiac illnesses.
Study on Divya Livogrit
Drawing inspiration from medicinal remedies in Ayurveda, Divya Livogrit, which contains herbal formulations of punarnava and bhumi amla, was used. Research was conducted to verify Divya Livogrit’s effectiveness and safety, and determine if its usage improves liver function and treat DILI.
For the study, human liver cells were cultivated and then exposed to carbon tetrachloride (CCl₄), an industrial chemical and a major cause behind DILI. When exposed, the cells’ capability is lowered. It signals the start of cellular death due to the introduction of oxidative stress and lowering of the mitochondria, or cellular powerhouse's, membrane potential. But Livogrit improved cellular renewal.
In the following nine-week in vitro research phase, Wistar rats were chosen. Several physiological constraints were observed. Dispensing Sarvakalp Kwath or Divya Livogrit lowered those parameters in a dose- and time-dependent way. The serum bilirubin parameter, usually checked during jaundice cases, showed high levels of dispersion of CCl₄. These levels lessened with Livogrit in a dose-dependent manner. The stress-induced high cholesterol and uric acid levels were treated. There was research conducted on silymarin, which is a strong allopathic drug for effect comparison. The results of the respective impacts on liver cells showed the effectiveness of Livogrit.
The CCl4 treatment encourages many pathologies in these liver cells. With the administration of Livogrit in the right dosage and duration, it significantly lowered the cellular oddities. The overall studies called Sarvakalp Kwath, or Livogrit an effective therapeutic agent.
Further Studies
To discover the safety and toxicology as per the regulatory and OECD guidelines, a dosage of 1000 mg/kg was given daily for 28 days. No bad effects were seen. The histopathological inspections of vital organs discovered that Divya Livogrit doesn’t result in side effects of those pathological changes. In the detailed analyses of red and white blood cells and 118 other diverse physical constraints, the defined results found Livogrit to be a safe and effective medicine.
3 Tips for Liver Health
Food: Leafy or bitter foods help cleanse the liver. Avoid processed or fatty foods and caffeine for their toxic content. Daily warm lemon water also helps purify.
Herbs: Turmeric, cumin, ginger, triphala and kalmegh lower inflammation and body fat, and aid in detoxification.
Lifestyle: Massage the body with warm sesame oil for circulation and cleansing. Yogasanas like Bhujanagasana rouse the liver.
Despite detailed material on medicinal plants and herbs in our ancient scriptures, less expertise in the classical languages used to write these texts meant the data slowly got lost in India. Patanjali is steadfast in keeping this heritage alive, and Divya Livogrit serves as a compelling example of this promise. Backed by rigorous research and modern validation, Divya Livogrit stands out as a significant, evidence-based solution for liver health.
