What's Happening?
Orasis Pharmaceuticals has released new data demonstrating that its presbyopia treatment, Qlosi (pilocarpine hydrochloride ophthalmic solution) 0.4%, is pupil selective. The study, conducted by the Bascom Palmer Eye Institute, showed that Qlosi significantly reduces pupil diameter without affecting ciliary muscle movement, similar to a balanced salt solution control. This finding supports the use of Qlosi as a safe and effective treatment for presbyopia, a condition affecting over 128 million people in the U.S. The data was presented at the Hawaiian Eye & Retina 2026 Conference.
Why It's Important?
Presbyopia is a common age-related condition that affects near vision, and current treatment options can be invasive or cumbersome. The new data on Qlosi offers a promising
non-invasive alternative that could improve the quality of life for millions of individuals. By demonstrating minimal adverse effects and maintaining efficacy, Qlosi could become a preferred treatment option, potentially reducing the need for more invasive procedures and expanding the market for presbyopia treatments.
What's Next?
Orasis Pharmaceuticals may seek to expand the availability of Qlosi through further clinical trials and regulatory approvals. The company could also explore partnerships to enhance distribution and accessibility. As the population ages, the demand for effective presbyopia treatments is likely to increase, positioning Orasis to capture a significant share of this growing market.
Beyond the Headlines
The development of Qlosi highlights the importance of innovation in addressing age-related health issues. It also reflects broader trends in the pharmaceutical industry towards developing treatments that offer both efficacy and safety. As more people seek non-invasive solutions for vision correction, products like Qlosi could lead to shifts in how presbyopia is managed and treated.









