What's Happening?
At the ESMO 2025 conference, Michael Lahn, Chief Medical Officer at iOnctura, discussed the role of allosteric modulation in oncology. iOnctura is a clinical-stage company focused on developing first-in-class small molecules to treat neglected and hard-to-treat cancers. Lahn highlighted the potential of allosteric modulation and autotaxin inhibition as promising approaches in cancer treatment. The conference served as a platform for sharing advancements in precision oncology and exploring innovative therapeutic strategies. Lahn's insights contribute to the ongoing dialogue about improving cancer treatment through novel mechanisms.
Why It's Important?
The discussion of allosteric modulation at ESMO 2025 underscores the importance of innovative approaches in the fight
against cancer. As traditional treatments face limitations, new strategies like allosteric modulation offer hope for more effective therapies, particularly for cancers that are difficult to treat. This focus on precision oncology reflects a broader shift towards personalized medicine, which aims to tailor treatments to individual patient profiles. The advancements discussed at the conference could lead to significant improvements in patient outcomes and potentially reduce the burden of cancer on healthcare systems.












