What's Happening?
Centauri Therapeutics, an immunotherapy company, has extended its Series A funding round to £30 million with a £6 million investment from the AMR Action Fund. This funding will support the progression of Centauri's lead clinical candidate, CTX-187, which
is part of the ABX-01 program targeting Gram-negative bacterial infections. The investment will facilitate the completion of Phase I clinical studies and prepare for Phase II. The AMR Action Fund, the largest venture capital fund focused on antimicrobial therapeutics, aims to address the growing challenge of drug-resistant infections. Dr. Henni-Karoliina Ropponen from the AMR Action Fund has been appointed to Centauri's Board of Directors.
Why It's Important?
The investment in Centauri Therapeutics is significant as it addresses the urgent need for new antimicrobial treatments amid rising drug-resistant infections. Gram-negative bacteria are particularly challenging due to their resistance to multiple drugs, posing a severe threat to global health. By advancing CTX-187, Centauri aims to provide new therapeutic options for patients with limited treatment choices. The involvement of the AMR Action Fund underscores the importance of developing innovative solutions to combat antimicrobial resistance, which is a critical issue for public health systems worldwide.
What's Next?
Centauri Therapeutics plans to use the new funding to complete Phase I clinical trials for CTX-187, gathering essential safety data. Following this, the company will prepare for Phase II studies, which will further evaluate the efficacy and safety of the drug. The success of these trials could lead to broader clinical applications and potentially new treatments for drug-resistant infections. The continued support from investors and stakeholders will be crucial as Centauri navigates the regulatory and developmental challenges ahead.









