Ascorbic acid, commonly known as vitamin C, is a crucial nutrient that plays a significant role in maintaining human health. This water-soluble compound is essential for preventing scurvy, a disease caused
by vitamin C deficiency. Beyond its role in nutrition, ascorbic acid is widely recognized for its antioxidant properties, making it a valuable addition to food products and dietary supplements.
Nutritional Importance and Deficiency
Ascorbic acid is an essential nutrient for humans and many animals, required for various biochemical processes. It is a vitamer of vitamin C, occurring naturally in many foods, particularly fruits and vegetables. The deficiency of vitamin C leads to scurvy, a condition characterized by fatigue, weakness, and connective tissue deterioration. Historically, scurvy was a major disease among sailors on long sea voyages, highlighting the importance of vitamin C in the diet.
The term ascorbic is derived from its antiscorbutic properties, emphasizing its role in combating scurvy. Ascorbic acid is used as a dietary supplement to ensure adequate intake and prevent deficiency, supporting overall health and well-being.
Antioxidant Properties and Applications
Ascorbic acid is renowned for its antioxidant capabilities, acting as a mild reducing agent. It readily donates hydrogen atoms to free radicals, forming the radical anion semidehydroascorbate. This reaction helps neutralize reactive oxygen species, which can damage nucleic acids, proteins, and lipids. By terminating chain radical reactions, ascorbic acid prevents cellular damage and supports healthy aging.
In the food industry, ascorbic acid and its salts, such as sodium, potassium, and calcium ascorbate, are used as antioxidant additives. These compounds are water-soluble, making them effective in preventing oxidation and discoloration in food products. Fat-soluble esters like ascorbyl palmitate and ascorbyl stearate are used to protect fats from oxidation.
Biological and Industrial Significance
Biologically, ascorbic acid is absorbed from the intestine through a sodium-dependent active transport process. It plays a vital role in collagen synthesis, wound healing, and immune function. Its antioxidant properties are crucial for maintaining cellular health and preventing oxidative stress.
Industrially, ascorbic acid is synthesized from glucose through various processes, including the Reichstein process. It is widely used in food preservation, approved under various E numbers, and is a staple in dietary supplements.
Ascorbic acid's dual role as a nutrient and antioxidant underscores its importance in both health and industry. Its ability to prevent scurvy and combat oxidative stress makes it an indispensable component of modern nutrition.








