Bakuchiol, a compound gaining popularity in skincare, has a rich history rooted in traditional medicine. First isolated in 1966, Bakuchiol is derived from the seeds of the Psoralea corylifolia plant, known in Sanskrit as Bakuchi. This article delves into the historical journey of Bakuchiol, from its initial discovery to its use in traditional medicine.
Historical Discovery
Bakuchiol was first isolated by Mehta and colleagues in 1966 from the seeds of Psoralea corylifolia.
The compound was named after the Sanskrit name of the plant, Bakuchi, highlighting its cultural significance. Psoralea corylifolia is a plant widely used in Indian Ayurveda, a traditional system of medicine, to treat various diseases. The isolation of Bakuchiol marked a significant milestone in understanding the chemical properties of this plant.
The discovery of Bakuchiol was not limited to Psoralea corylifolia. It has also been isolated from other plants such as P. grandulosa, P. drupaceae, Ulmus davidiana, Otholobium pubescens, Piper longum, and Aerva sangulnolenta Blum. This widespread occurrence in different plant species underscores its importance and potential in various medicinal applications.
Traditional Uses
In traditional Indian and Chinese medicine, Psoralea corylifolia has been used to treat a variety of ailments. The seeds of this plant, rich in Bakuchiol, have been utilized for their therapeutic properties. Bakuchiol's presence in these seeds contributes to the plant's effectiveness in traditional remedies.
The use of Psoralea corylifolia in Ayurveda highlights the cultural and medicinal significance of Bakuchiol. This traditional system of medicine has long recognized the benefits of the plant, incorporating it into treatments for skin conditions and other health issues. The historical use of Bakuchiol in these practices provides a foundation for its modern applications.
Modern Applications
Despite its historical roots, Bakuchiol's commercial use in topical applications did not occur until 2007. It was introduced to the market under the trade name Sytenol A by Sytheon Ltd. This marked a new era for Bakuchiol, transitioning from traditional medicine to modern skincare.
Bakuchiol's introduction to the skincare market reflects its growing popularity and recognition as a beneficial compound. Its antioxidant, anti-inflammatory, and antibacterial properties make it a valuable addition to skincare products. The historical journey of Bakuchiol, from its discovery to its modern applications, showcases its enduring relevance and potential.












