Niacinamide's Role
Niacinamide, a water-soluble vitamin B, prevents melanosome transfer, helping reduce pigmentation. However, it's not a direct tyrosinase inhibitor. Studies
show 4–5% niacinamide can improve pigmentation over 8–12 weeks. But alone, it may not be enough for deep spots, melasma, or sun damage. It acts more as a supporting actor than the leading role.
Beyond Niacinamide: Key Ingredients
For significant improvement, dermatologists often recommend a multi-agent approach. Tretinoin increases cell turnover and enhances the penetration of other actives. Kojic acid (1-2%) directly inhibits melanin synthesis, and arbutin (2-5%) inhibits tyrosinase without the harshness of hydroquinone. Tranexamic acid disrupts the interaction between keratinocytes and melanocytes.
Unlocking Optimal Efficacy
To truly tackle those dark spots, combining ingredients is key. Consider incorporating tretinoin to boost cell turnover, and kojic acid to hinder melanin creation. Arbutin, another melanin inhibitor, can be added to your daily routine to give you that desired glow. Tranexamic acid can be your final weapon to reduce inflammation.
Building Your Skincare Routine
Start with a gentle cleanser and follow with your chosen actives, allowing each to absorb fully. Tretinoin is best used in the evening, while kojic acid, arbutin and niacinamide can be included in your day or night routine. Don't forget a broad-spectrum sunscreen during the day! A perfect routine is a secret mantra for spotless skin.
