By Niket Nishant and Tharuniyaa Lakshmi
Sept 15 (Reuters) - Major U.S. stock indexes were set to open lower on Tuesday as higher crude prices, elevated Treasury yields and an uncertain outlook for AI demand kept investors at bay.
Several tech stocks sank premarket, with Alphabet and Microsoft down around 1% each. Chipmakers, which bore the brunt of Monday's selloff, were trading within a narrow range. Nvidia rose 0.7%.
The latest bout of anxiety was driven by calls from top AI companies to slow the
development of the technology, citing safety concerns.
While there is little clarity so far on how such a slowdown would work, the declines have added to the gloom in markets at a time when above-target inflation and fears of higher borrowing costs have already clouded the backdrop for equities.
"Delays are not good on Wall Street. Any sort of slowdown would be a problem. But I think at this point, the market doesn't believe there will be a slowdown," said Joe Saluzzi, co-founder and co-head of equity trading at Themis Trading.
"There's just too many competitive factors, and some of these companies want to go public. You're not going public unless you're showing some earnings and growth."
Meanwhile, the Federal Reserve is expected to raise interest rates, with traders pricing in a 92.5% chance of a hike on Wednesday.
At 08:32 a.m. ET, Dow E-minis were down 144 points, or 0.27%, S&P 500 E-minis fell 12 points, or 0.16%, and Nasdaq 100 E-minis lost 39 points, or 0.13%.
OIL PRICES WEIGH
The Middle East conflict has shown few signs of easing, keeping oil prices elevated and deepening concerns of a supply shock.
Brent crude futures rose 0.6% to $106.31, while U.S. West Texas Intermediate futures were trading at $102.59, also up 1.2%.
"Energy is doing most of the damage on the inflationary front at present," said Anthony Saglimbene, chief market strategist at Ameriprise Financial.
The yield on the benchmark U.S. 10-year Treasury note hit its highest since 2007, as investors girded for what many suspect will be just the first in a series of rate increases. It was last up 5.3 basis points at 5.0122%.
High yields on risk-free Treasuries dampen the appeal of stocks.
The latest batch of economic data has also given little comfort to investors. The Labor Department's report last week showed consumer prices accelerated in August, while a key measure of underlying inflation posted its largest increase in four months.
"Given current inflation dynamics, a solid employment backdrop, and a new Fed Chair looking to establish credibility, Wednesday's rate decision carries the highest odds of a hike markets have seen all year," Saglimbene said.
"Investors should be prepared for the Committee to act this week, even if there's still a small chance Fed Chair (Kevin) Warsh and company decide to stand pat."
Elsewhere, shares of Dave & Buster's tumbled over 13% premarket after second-quarter revenue missed expectations.
Waystar rose 12% after Reuters reported the healthcare software firm is exploring options, including a potential sale.
(Reporting by Niket Nishant and Tharuniyaa Lakshmi in Bengaluru; Editing by Mrigank Dhaniwala and Devika Syamnath)
