What's Happening?
Researchers have successfully used CRISPR gene editing to create pigs that are completely resistant to classical swine fever, a significant disease affecting livestock worldwide. This genetic modification involves altering a single amino acid in a pig protein,
which prevents the virus from replicating. The gene-edited pigs showed no signs of infection when exposed to the virus, unlike their non-edited counterparts. This breakthrough could also be applied to cattle and sheep, potentially making them resistant to related viruses. The development is seen as a major step towards sustainable livestock production, reducing the need for laborious and costly vaccination processes.
Why It's Important?
The introduction of gene-edited pigs resistant to swine fever could revolutionize the livestock industry by enhancing animal welfare and increasing productivity. This advancement may lead to lower greenhouse gas emissions and reduced costs for consumers. The ability to produce disease-resistant livestock could also strengthen food security and reduce economic losses associated with disease outbreaks. However, the commercialization of these pigs will depend on regulatory approvals, which vary by country. The success of this technology could pave the way for broader acceptance and application of gene editing in agriculture.
What's Next?
The company Genus, which funded part of the research, is considering commercializing the gene-edited pigs. Regulatory approval processes are underway in several countries, including the US, Brazil, and Japan. The outcome of these approvals will determine the timeline for bringing these pigs to market. Additionally, further studies are needed to ensure that the genetic modifications do not adversely affect animal welfare. The research team is also exploring the application of this gene-editing technique to cattle and sheep, which could further expand its impact on the livestock industry.
