What's Happening?
Researchers at Aalto University have developed a promising new laser treatment aimed at slowing or halting the progression of dry age-related macular degeneration (AMD). This condition affects the retina
and leads to central vision loss, impacting approximately 20 million adults aged 40 and older in the United States. The treatment involves applying controlled heat to the affected retinal tissue, which activates the eye's natural repair mechanisms. The process uses near-infrared light to safely warm the tissue, triggering the production of heat shock proteins and autophagy, which help refold damaged proteins and remove protein build-up. The technique has shown positive results in animal studies, and human clinical trials are set to begin in Finland in 2026.
Why It's Important?
Dry AMD is one of the most common causes of vision impairment among older adults, yet there is currently no effective treatment available. The development of this laser treatment could significantly impact the lives of millions of Americans by preserving their vision and improving their quality of life. The ability to activate the eye's natural repair processes offers a novel approach to managing this condition, potentially reducing healthcare costs associated with vision loss and enhancing patient independence. The research also highlights the importance of innovative medical technologies in addressing age-related diseases.
What's Next?
Human clinical trials for the laser treatment are scheduled to begin in Finland in the spring of 2026. The initial phase will focus on confirming the safety of the treatment, followed by determining the optimal frequency for lasting results. The research team has launched a spin-off company, Maculaser, to facilitate the clinical application of the therapy. If successful, the treatment could be available in hospital eye clinics within three years, with the ultimate goal of widespread availability at local ophthalmologists.
Beyond the Headlines
The development of this laser treatment underscores the potential for medical advancements to address age-related conditions through non-invasive methods. The use of controlled heat to activate cellular repair mechanisms may pave the way for similar treatments in other degenerative diseases, highlighting the intersection of technology and healthcare innovation.
