What is the story about?
What's Happening?
Researchers from Mass General Brigham have conducted a study indicating that cocoa extract supplements, rich in cocoa flavanols, can lower inflammation markers in aging adults. The study, part of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS), tracked five markers of inflammation linked to aging in participants who took daily cocoa extract supplements over several years. The results showed a decline in levels of hsCRP, an inflammatory protein associated with higher cardiovascular risk, suggesting an anti-inflammatory effect that may protect heart health. The study, published in Age and Ageing, highlights the potential of nutritional strategies to slow age-related inflammation, often referred to as 'inflammaging'.
Why It's Important?
The findings from the COSMOS trial underscore the potential of cocoa extract supplements in reducing age-related inflammation, which is linked to cardiovascular disease. This research is significant as it suggests a nutritional approach to managing inflammaging, a condition that can harden arteries and lead to cardiovascular issues. The study's results could influence public health strategies, encouraging the inclusion of plant-based foods rich in flavanols, such as cocoa, in diets to promote cardiovascular health. The decrease in hsCRP levels may explain the cardio-protective effects observed in the trial, offering a promising avenue for reducing cardiovascular disease mortality among older adults.
What's Next?
Researchers plan to continue evaluating the COSMOS trial to determine whether cocoa extract and multivitamin regimens can curb more severe inflammaging and other aging-related health outcomes. The study calls for further investigation into the role of plant-based foods in cardiovascular health, particularly those rich in flavanols. Future research may explore the increase in interferon-γ, an immune-related cytokine observed in the study, to understand its implications for inflammation modulation. The team aims to build on these findings to develop comprehensive nutritional strategies for healthy aging.
Beyond the Headlines
The study highlights the importance of a diverse, colorful, plant-based diet in managing inflammation and promoting cardiovascular health. It reinforces the potential of cocoa products rich in flavanols as part of a healthy lifestyle. The research also opens new questions regarding the role of immune-related cytokines in inflammation modulation, suggesting avenues for future exploration in the field of aging and cardiovascular health.
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