What's Happening?
Researchers at the University of Pennsylvania have developed a method to train dogs to detect hemangiosarcoma, a malignant cancer of blood vessel cells, by scent. This type of cancer is often not diagnosed until it is too late, making early detection
crucial. The study, led by Cynthia M. Otto and her team at the School of Veterinary Medicine, involved training five bio-detection dogs to recognize the scent of hemangiosarcoma through volatile organic compounds. These compounds are what dogs detect at much lower levels than humans. The dogs participated in double-blinded tests with blood serum samples from dogs with confirmed hemangiosarcoma, diseased controls, and healthy controls. The dogs correctly identified the cancer samples 70% of the time, a promising result that suggests hemangiosarcoma has a detectable scent profile.
Why It's Important?
The ability to detect hemangiosarcoma early could significantly improve treatment outcomes for dogs, as this cancer is often diagnosed too late for effective intervention. Early detection could allow for preventative measures, such as removing the spleen before it ruptures or starting chemotherapy sooner. This research not only offers hope for better canine health outcomes but also opens the door for developing a machine or test for early cancer detection. Such advancements could lead to annual screenings, flagging potential issues for further testing and potentially saving lives. The study's success also highlights the broader potential of using trained dogs in medical diagnostics, which could extend to other diseases in both animals and humans.
What's Next?
Future research will focus on translating these findings into a practical screening tool that veterinarians can use. This could involve developing a machine that mimics the dogs' ability to detect the cancer scent. Additionally, early detection would allow researchers to test different therapies in clinical trials, potentially leading to new treatment options. The study's success may also encourage further exploration into the use of bio-detection dogs for other medical conditions, expanding the role of animals in healthcare diagnostics.
