What's Happening?
A study has identified a multidrug-resistant strain of Acinetobacter beijerinkii, named MPE71, isolated from the marine plastisphere. This strain exhibits high-level resistance to polymyxin B, a last-resort
antibiotic. The research highlights the strain's genetic makeup, which includes numerous multidrug efflux pump genes, contributing to its resistance. The study utilized genomic and transcriptomic analyses to understand the resistance mechanisms, revealing enhanced membrane biosynthesis and efflux pump activity. This discovery marks the first report of such resistance in marine Acinetobacter, emphasizing the ecological risk posed by antibiotic resistance in marine environments.
Why It's Important?
The emergence of antibiotic-resistant bacteria in marine environments poses significant public health risks, as these strains can potentially transfer resistance genes to human pathogens. The study underscores the need for monitoring and managing antibiotic resistance in non-clinical settings, such as marine ecosystems. The findings could influence public health policies and strategies aimed at controlling the spread of resistant bacteria. Additionally, the research highlights the importance of developing new antibiotics and alternative treatments to combat resistant strains.
