What's Happening?
A recent study has raised concerns about the long-term use of melatonin supplements, suggesting a potential link to increased risk of heart failure and mortality. The study, which reviewed health records of over 130,000 adults with insomnia, found that
individuals who used melatonin for more than a year had a higher likelihood of being diagnosed with heart failure, hospitalized for heart failure, or dying from any cause compared to non-users. The findings will be presented at the American Heart Association’s Scientific Sessions 2025. Melatonin, a hormone produced by the pineal gland, is commonly used to aid sleep and is available over-the-counter in the U.S. However, the study highlights the need for further research into its cardiovascular safety.
Why It's Important?
The study's findings could have significant implications for public health, particularly for the millions of Americans who use melatonin as a sleep aid. If confirmed, these results may lead to changes in how healthcare providers counsel patients regarding the use of melatonin, potentially affecting the supplement industry and consumer behavior. The research underscores the importance of understanding the long-term effects of widely used supplements, especially those perceived as safe and natural. This could prompt regulatory scrutiny and influence future guidelines on melatonin use.
What's Next?
Further research is needed to establish a direct cause-and-effect relationship between melatonin use and heart health. The study's authors call for more comprehensive investigations to test melatonin's safety for the heart. Healthcare providers may begin to reconsider prescribing melatonin for chronic use, and patients might seek alternative sleep aids. The findings could also lead to increased monitoring and regulation of over-the-counter supplements in the U.S.
Beyond the Headlines
The study highlights a broader issue of the unregulated nature of dietary supplements in the U.S., where variations in product purity and dosage can occur. This raises ethical questions about consumer safety and the responsibility of manufacturers to ensure product consistency. The potential health risks associated with long-term melatonin use may also prompt discussions about the need for more stringent oversight and labeling requirements.
